References

Abrahamson, S. 1991. The dominance of research in staffing of medical schools: Time for a change? Lancet 337:1586-1588.

Agency for Health Care Policy and Research (AHCPR). 1992. Program, Evaluation, and Legislation Plan, FY 1994-1998. OPD 2/92. Rockville, Md.

Ahrens, E.H. 1992. The Crisis in Clinical Research: Overcoming Institutional Obstacles. New York: Oxford University Press.

Alcohol, Drug Abuse, and Mental Health Administration. 1991. ADAMHA Extramural Activities. ADAMHA Program Analysis Report No. 91-23. Rockville, Maryland.

American Federation for Clinical Research. 1992. Draft recommendations on policy issues to be considered in the NIH strategic plan. Clin. Res. 40:189-196.

American Medical Association (AMA). 1991. Women in Medicine in America: In the mainstream. Chicago.

American Medical Association (AMA). 1992. Physician Characteristics and Distribution in the U.S. G. Roback, L. Randolph, and B. Seidman, eds. Chicago.

Antman K., L. Schnipper, and E. Frei III. 1988. The crisis in clinical cancer research: Third-party insurance and investigational therapy. N. Engl. J. Med. 319:46-48.

Antman, K., L.M. Aledort, J. Yarbro, et al. 1989. Cost-effectiveness and reimbursement in patient care. Semin. Hematol. 26:32-45.

Applegate, W.B. 1990. Career development in academic medicine. Am. J. Med. 88:263-267.

Arias, I.M. 1989. Training basic scientists to bridge the gap between basic science and its application to human disease. N. Engl. J. Med. 321:972-974.

Association of American Medical Colleges (AAMC). 1984. Physicians for the twenty-first century. Report of the Project Panel on the General Professional Education of the Physician and College Preparation for Medicine (GPEP). Part II. J. Med. Educ. 59(suppl.)



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Careers in Clinical Research: Obstacles and Opportunities References Abrahamson, S. 1991. The dominance of research in staffing of medical schools: Time for a change? Lancet 337:1586-1588. Agency for Health Care Policy and Research (AHCPR). 1992. Program, Evaluation, and Legislation Plan, FY 1994-1998. OPD 2/92. Rockville, Md. Ahrens, E.H. 1992. The Crisis in Clinical Research: Overcoming Institutional Obstacles. New York: Oxford University Press. Alcohol, Drug Abuse, and Mental Health Administration. 1991. ADAMHA Extramural Activities. ADAMHA Program Analysis Report No. 91-23. Rockville, Maryland. American Federation for Clinical Research. 1992. Draft recommendations on policy issues to be considered in the NIH strategic plan. Clin. Res. 40:189-196. American Medical Association (AMA). 1991. Women in Medicine in America: In the mainstream. Chicago. American Medical Association (AMA). 1992. Physician Characteristics and Distribution in the U.S. G. Roback, L. Randolph, and B. Seidman, eds. Chicago. Antman K., L. Schnipper, and E. Frei III. 1988. The crisis in clinical cancer research: Third-party insurance and investigational therapy. N. Engl. J. Med. 319:46-48. Antman, K., L.M. Aledort, J. Yarbro, et al. 1989. Cost-effectiveness and reimbursement in patient care. Semin. Hematol. 26:32-45. Applegate, W.B. 1990. Career development in academic medicine. Am. J. Med. 88:263-267. Arias, I.M. 1989. Training basic scientists to bridge the gap between basic science and its application to human disease. N. Engl. J. Med. 321:972-974. Association of American Medical Colleges (AAMC). 1984. Physicians for the twenty-first century. Report of the Project Panel on the General Professional Education of the Physician and College Preparation for Medicine (GPEP). Part II. J. Med. Educ. 59(suppl.)

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Association of American Medical Colleges (AAMC). 1987. Research Activity of Full-Time Faculty in Departments of Medicine. Washington, D.C. Association of American Medical Colleges (AAMC). 1991. Financing a Medical Education in the '90s: Collective Concerns—Paying the Bills and Preventing Defaults. Washington, D.C. Association of American Medical Colleges (AAMC). 1992a. AAMC Data Book: Statistical Information Related to Medical Education. P. Jolly and D.M. Hudley, eds. Washington, D.C. Association of American Medical Colleges (AAMC). 1992b. Educating Medical Students. Washington, D.C. Association of American Medical Colleges (AAMC). 1993. U.S. Medical School Faculty 1993 . Washington, D.C. Atkins, D., R.A. Deyo, R.K. Albert, D.J. D.J. Sherrard, and T.S. Inui. 1994. Models of postdoctoral training for clinical research. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Austrian, R, G.S. Mirick, D.E. Rogers, et al. 1951. The efficacy of modified oral penicillin therapy of pneumococcal lobar penumonia. Bull. Johns Hopkins Hosp. 88:264-269. Batshaw, M.L., L.P. Plotnick, B.G. Petty, et al. 1988. Academic promotion at a medical school: Experience at Johns Hopkins University School of Medicine. N. Engl. J. Med. 318:741-747. Battelle. 1991. The Value of Pharmaceuticals: An Assessment of Future Costs for Selected Conditions. Washington, D.C.: Battelle Human Affairs Research Centers. Beaty, H.N., D. Babbott, E.J. Higgins, P. Jolly, and G.S. Levey. 1986. Research activities of faculty in academic departments of medicine. Ann. Intern. Med. 104:90-97. Beran, R.L. 1994. Considerations of educational debt and the selection of clinical research careers. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Bickel, J. 1988. Women in medical education. N. Engl. J. Med. 319:1579-1584. Bickel, J. 1991. The changing faces of promotion and tenure at U.S. medical schools. Acad. Med. 66:249-256. Bickel, J., and B.E. Whiting. 1991. AAMC data report: Comparing the representation and promotion of men and women faculty at U.S. medical schools. Acad. Med. 268:173. Bickel, J.W., C.R. Sherman, J. Ferguson, et al. 1981. The role of M.D.-Ph.D. training in increasing the supply of physician-scientists. N. Engl. J. Med. 304:1265-1268. Biddle, A.K., G.M. Carter, J.S. Uebersax, and J.D. Winkler. 1988. Research Careers of Recipients of the Research Scientist and Research Scientist Development Awards. Publication No. R-3688-NIMH. Bethesda, M.D.: National Institute of Mental Health. Bishop, M.J. 1984. Infuriating tensions: Science and the medical student. J. Med. Educ. 59:91-102. Blackburn, R.T. 1979. Academic careers: Patterns and possibilities. Curr. Issues Higher Educ. 2:25-27.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Blake, D.A. 1992. The opportunities and problems of commercial ventures: The university view. Pp. 88-92 in Biomedical Research: Collaboration and Conflict of Interest. R. Porter and T.E. Malone, eds. Baltimore: Johns Hopkins University Press. Blake, D.A. 1994. University-industry relationships in clinical research: University perspective. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Bland, C.J., and C.C. Schmitz. 1986. Characteristics of the successful researcher and implications for faculty development. J. Med. Educ. 61:22-33. Blank, L. 1993. Roles and responsibilities of resident review committees and certification boards in promoting research careers. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Blumenthal, D. 1992. Academic-industry relationships in the life sciences: Extent, consequences, and management. J. Am. Med. Assoc., 268:3344-3349. Blumenthal, D., M. Gluck, K.S. Louis, and D. Wise. 1986a. Industrial support of university research in biotechnology. Science 231:242-246. Blumenthal, D., M. Gluck, K.S. Louis, M.A. Stoto, and D. Wise. 1986b. University-industry relationships in biotechnology: Implications for the university. Science 232:1361-1366. Boniface, Z.E., and R.W. Rimel. 1987. U.S. Funding of Biomedical Research. Philadelphia: The Pew Charitable Trusts. Boyer, E.L. 1990. Scholarship reconsidered: Priorities of the professoriate. Princeton, N.J.: The Carnegie Foundation for the Advancement of Teaching. Bradford, W.D., S. Pizzo, and A.C. Christakos. 1986. Careers and professional activities of graduates of a medical scientist training program. J. Med. Educ. 61:915-918. Brancati, F.L., L.A. Mead, D.M. Levine, et al. 1992. Early predictors of career achievement in academic medicine. J. Am. Med. Assoc. 267:1372-1376. Bryan, G.T. 1991. Physicians and medical education. J. Am. Med. Assoc., 266:1407-1408. Burke, D.L. 1992. Physicians in the academic marketplace. Westport, Conn. : Greenwood. Burke, J.D., H.A. Pincus, and H. Pardes. 1986. The clinician researcher in psychiatry. Am. J. Psychiatry 143:968-974. Bush, V. 1945. Science--The Endless Frontier, A Report to the President on a Program for Postwar Scientific Research. Washington, D.C.: Office of Scientific Research and Development. (Reprinted by the National Science Foundation, Washington, D.C., May 1980.) Cameron, S.W. 1981. Sponsorship and academic career success. J. Higher Educ. 52:369-377. Cadman, E.C. 1990. The new physician-scientist: A guide for the 1990s. Clin. Res. 38:191-198. Cadman, E.C. 1994. The image of the clinical investigator. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. California Institute of Technology (CIT). 1991. Summer Undergraduate Research Fellowships, 1991 Annual Report. Pasadena, Calif. Calkins, E.V., and R. Wakeford. 1982. Perceptions of instructors and students of instructors' roles. J. Med. Educ. 58:967-969.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Cantor, J.C., A.B. Cohen, D.C. Barker, et al. 1991. Medical educators' views on medical education reform. J. Am. Med. Assoc. 265:1002-1006. Carnegie Commission on Science, Technology, and Government. 1992. Enabling the Future: Linking Science and Technology to Societal Goals. Washington, D.C. Carter, G.M., A. Robyn, and A.M. Singer. 1983. The Supply of Physician Researchers and Support for Research Training. Part I. Evaluation of the Hartford Fellowship Program. Santa Monica, Calif.: The RAND Corporation. Carter, G.M., J.D. Winkler, and A.K. Bibble. 1987. An Evaluation of the NIH Research Career Development Award. Publication No. R-3568-NIH. Santa Monica, Calif.: The RAND Corporation. Chin, D., D. Hopkins, K. Melmon, and H. Holman. 1985. The relation of faculty academic activity to financing sources in a department of medicine. N. Engl. J. Med., 312:1029-1034. Choppin, P.W. 1989. Howard Hughes Medical Institute: Training the next generation of medical scientists. Acad. Med. 64:382-383. Cohen, R.A. 1991. New foundations for young investigators. Clin. Res. 39:505-513. Cole, J.R., and H. Zuckerman. 1987. Marriage, motherhood, and research performance in science. Sci. Am. 256:119-125. Commonwealth Fund. 1985. The future financing of teaching hospitals. In Prescription for Change: Report of the Task Force on Academic Health Centers. New York: Harkness. Cooper T. and M. Novitch. 1992. The research needs of industry working with academia and with the federal government. Pp. 187-198 in Biomedical Research: Collaboration and Conflict of Interest. R. Porter and T.E. Malone, eds. Baltimore: Johns Hopkins University Press. Cooperative Institutional Research Program. 1982 Cotton, P. 1992. Harassment hinders women's care and careers. J. Am. Med. Assoc., 267:778-783. Cotton, P. 1992. Women scientists explore more ways to smash through the ''glass ceiling." J. Am. Med. Assoc. 268:173. Cuca, J. 1983. NIH grant applications for clinical research: Reasons for poor ratings or disapproval. Clin. Res. 31:453-461. Cuca, J., and W.J. McLoughlin. 1987. Why clinical research grant applications fare poorly in review and how to recover. Cancer Invest. 5:55-58. Davis, W.K., and W.N. Kelley. 1982. Factors influencing decisions to enter careers in clinical investigation. J. Med. Educ. 57:275-281. Detsky, A.S. 1989. Are clinical trials a cost-effective investment? J. Am. Med. Assoc., 262:1795-1800. DiBona, G.F. 1979. Whence cometh tomorrow's clinical investigator's? Clin. Res. 27:253-256. DiMasi, J.A., R.W. Hansen, H. G. Grabowski, and L. Lasagna. 1991. Cost of innovation in the pharmaceutical industry. J. Health Econ. 10:107-142. Directory of Medical Specialists. 1991. Marquis Who's Who, 25th Edition. Willmette, Illinois: Macmillan Directory Division. Dwyer, M.M., A.A. Flynn, and P.S. Inman. 1991. Differential progress of women faculty: Status 1980-1990. In J.C. Smart, ed. Higher Education: Handbook on Theory and Research, Volume 3. New York: Agathon Press. Eddy, D.M. 1984. Variations in physician practice: The role of uncertainty. Health Affairs 4:74-89.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Educational Testing Service. 1988. National Assessment of Educational Progress: The Science Report Card: Elements of Risk and Recovery. Princeton, N.J. Eisenberg, D. 1989. Medicine is no longer a man's profession. Or when the men's club goes coed, it's time to change the regs. N. Engl. J. Med. 321:1542-1544. Eisenberg, J.M. Cultivating a new field: Development of a research program in general internal medicine. J. Gen. Intern. Med. 1(Suppl.):S8-S18. Farrell, K., M. Witte, M. Holguin, and S. Lopez. 1985. Women physicians in medical academia: A national survey. J. Am. Med. Assoc. 254:781-787. Federal Coordinating Committee for Science, Engineering, and Technology (FCCSET), Committee on Education and Human Resources. 1991. By the Year 2000, First in the World. Washington, D.C.: White House Office of Science and Technology Policy. Feinstein, A.R. 1985. Additional basic approaches in clinical research. Clin. Res. 33:111-114. Feinstein, A.R. 1985. Clinical epidemiology: The architecture of clinical research. Philadelphia: W.B. Saunders. Fletcher, R.H. 1989. The costs of clinical trials. J. Am. Med. Assoc. 262:1842. Fletcher, R.H., S.W. Fletcher, and E.H. Wagner. 1982. Clinical Epidemiology: The Essentials. Baltimore: Williams & Wilkins. Flexner, A. 1910. Medical education in the United States and Canada. Bulletin No. 4. New York: Carnegie Foundation for the Advancement of Teaching. Forrest, J.N., Jr. 1980. The decline in the training of clinical investigators: Data and proposals from the 1970's. Clin. Res. 28:246-247. Four Schools Physician-Scientist Program in Internal Medicine. 1991. Information booklet. Baltimore. Fox, R.C., J.P. Swazey, and J.C. Watkins eds. 1992. The Study of the Sick. Proceedings of an Oral History Conference on the Development of Clinical Research. Philadelphia: The Medical College of Pennsylvania. Freireich, E.J. 1990. A study of the status of clinical cancer research in the United States. J. Natl. Cancer Inst. 83:829-837. Frieden, C., and B.J. Fox. 1991. Career choices of graduates from Washington University's medical scientist training program. Acad. Med. 66:162-164. Friedman. M.A. 1987. Patient accrual to clinical trials. Cancer Treatment Rep. 71:557-558. Friedman, M.A., D.F. Cain, D. Bronzert, and R.S. Wu. 1991. Poor funding rates of cancer clinical research: Intractable problem or solvable challenge. J. Natl. Cancer Inst. 83:838-841. Fye, W.B. 1991. The origin of the full-time faculty system. Implications for clinical research. J. Am. Med. Assoc. 265:1555-1561. Garrison, H.H., and P.W. Brown. 1985. Minority Access to Research Careers: An Evaluation of the Honors Undergraduate Research Training Program. Institute of Medicine. Washington, D.C.:National Academy Press. Garrison, H.H., and P.W. Brown. 1986. The Career Achievements of NIH Postdoctoral Trainees and Fellows. Washington, D.C.: National Academy Press. George, Y.S. 1991. Investing in the Human Potential: Science and Engineering at the Crossroads . M.L. Matyas and S.M. Malcom, eds. Washington, D.C.: American Association for the Advancement of Science. George, Y.S., B. Chu-Clewell, and N. Watkins. 1987. Lessons for HBCUs from Precollege Science and Mathematics Programs. Washington, D.C.: White House Initiative on Historically Black Colleges and Universities.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Giamatti, A.B. 1983. Free market and free inquiry: The university, industry, and cooperative research. Pp. 3-9 in Partners in the Research Enterprise: University-Corporate Relations in Science and Technology. T.W. Langfitt, S. Hackney, A.P. Fishman, and A.V. Glowasky, eds. Philadelphia:University of Pennsylvania Press. Gill, G. 1984. The end of the physician-scientist? Am. Scholar 53:353-368. Ginzberg, E., and A.B. Dutka. 1989. The Financing of Biomedical Research. Baltimore:The Johns Hopkins University Press. Glickman, R.M. 1985. The future of the physician-scientist. J. Clin. Invest. 76:1293-1296. Gluck, M., D. Blumenthal, and M. Stoto. 1987. University-industry relationships in the life sciences: Implications for students and postdoctral fellows. Res. Policy 16:327-336. Goldman, L. 1991. Blueprint for a career in general internal medicine. J. Gen. Intern. Med. 6:331-334. Goldman, L., E.F. Cooke, J. Orav, A.M. Epstein, A.L Komaroff, T.L. Delbanco, A.G. Mulley, and H.H. Hiatt. 1990. Research training in clinical effectiveness: Replacing "In my experience. … with rigorous clinical investigation. Clin. Res. 38:686-693. Goldman, L., S. Shea, M. Wolf, and E. Braunwald. 1986. Clinical research training in parallel: The internal medicine research residency track at the Brigham and Women's Hospital. Clin. Res. 34:1-5. Goldstein, J.L. 1986. On the Origin and Prevention of PAIDS (Paralyzed Academic Investigator's Disease Syndrome). Presidential address delivered before the 78th Annual Meeting of the American Society for Clinical Investigation, Washington, D.C., May 3, 1986. J. Clin. Invest 78:848-854. Goodman, L.J., E.E. Brueschke, R.C. Bone, et al. 1991. An experiment in medical education: A critical analysis using traditional criteria. J. Am. Med. Assoc. 265:2373-2376. Grant, L. 1988. The gender climate of medical school. J. Am. Med. Women's Assoc. 43:109-119. Graves, P., and C. Thomas. 1985. Correlates of midlife career achievement among women physicians. J. Am. Med. Assoc. 254:781-787. Green, K.C. 1989. A profile of undergraduates in the sciences. Am. Sci. Sept/Oct:475-480. Greenlick, M.R. 1992. Educating physicians for population-based clinical practice. J. Am. Med. Assoc. 267:1645. Healy, B. 1988. Innovators for the 21st century: will we face a crisis in biomedical research brainpower. N. Engl. J. Med. 319:1058-1064. Herman, S.S., and A.M. Singer. 1986. Basic Scientists in Clinical Departments of Medical Schools. Clin. Res. 34:149-158. Hewitt, N.M., and E. Seymour. 1991. Factors contributing to high attrition rates among science, mathematics, and engineering undergraduate majors. Report to the Alfred P. Sloan Foundation. Boulder: University of Colorado. Holmes, B.L. 1992. Current strategies for the development of medical devices. In Medical Innovation at the Crossroads, Volume 3, Technology and Health Care in an Era of Limits. A.C. Geligns, ed. Washington, D.C.:National Academy Press. Howard Hughes Medical Institute. 1992. Attracting Students to Science, Undergraduate and Precollege Programs. Bethesda, Maryland.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Hughes, R.G., D.C. Barker, and R.C. Reynolds. 1991. Are we mortgaging the medical profession? N. Engl. J. Med. 325:404-407. Hunter, C.P., F.W. Frelick, A.R. Feldman, et al. 1987. Selection factors in clinical trials: Results from the community clinical oncology program physician's patient log. Cancer Treatment Rep. 71:559-565. Institute of Medicine. 1979. DHEW's Research Planning Principles: A Review. Washington, D.C.: National Academy of Sciences. Institute of Medicine. 1980. DHEW Health Research Planning, Phase II: A Review. Washington, D.C.: National Academy of Sciences. Institute of Medicine. 1985. Personnel Needs and Training for Biomedical and Behavioral Research. Washington, D.C.:National Academy Press. Institute of Medicine. 1987. Organization of NIH. Washington, D.C.: National Academy Press. Institute of Medicine. 1988a. Resources for Clinical Investigation. Washington, D.C.:National Academy Press. Institute of Medicine. 1988b. A Healthy NIH Intramural Program, Structural Change or Administrative Remedies? Washington, D.C.: National Academy Press. Institute of Medicine. 1989a. A Stronger Cancer Centers Program. Washington, D.C.: National Academy Press. Institute of Medicine. 1989b. Government and Industry Collaboration in Biomedical Research and Education. Washington, D.C.: National Academy Press. Institute of Medicine. 1989c. Physician Staffing for the VA, Volume 1. Washington, D.C.: National Academy Press. Institute of Medicine. 1989d. Biomedical and Behavioral Research Scientists: Their Training and Supply. Washington, D.C.: National Academy Press. Institute of Medicine. 1990. Funding Health Sciences Research: A Strategy to Restore Balance. Washington, D.C.: National Academy Press. Institute of Medicine. 1992. Strengthening Research in Academic OB/GYN Departments. Washington, D.C.: National Academy Press. Janowsky, D.S., I.D. Glick, L. Lash, et al. 1986. Psychobiology and psychopharmacology: Issues in clinical research training. J. Clin. Psychopharmacol. 6:1-7. Jennett, P. 1988. Medical school M.D. graduates' activities in research and teaching. In Research in Medical Education, 1988: Proceedings of the Twenty-Seventh Annual Conference, D.S. Dabney, compiler. Washington, D.C.: Association of American Medical Colleges. Jolin, L.D., P. Jolly, J.Y. Krakower, and R. Beran. 1992. US medical school finances. J. Am. Med. Assoc. 268:1149-1155. Jonas, H.S., S.I. Etzel, and B. Barzansky. 1991. Educational programs in U.S. medical schools. J. Am. Med. Assoc. 266:913-920. Jonas, H.S., S.I. Etzel, and B. Barzansky. 1992. Educational programs in U.S. medical schools. J. Am. Med. Assoc. 268:1083-1090. Jones, R.F., M.F. Mirsky, and J.A. Keyes, Jr. 1985. Clinical practice of medical school faculties: An AAMC survey of problems and issues. J. Med. Educ. 60:897-910. Kalichman, M.W., and P.J. Freidman. 1992. A pilot study of biomedical trainees' perceptions concerning research ethics. Acad. Med. 67:769-775. Kelley, W.N. 1980. A positive approach: Things could be even better. Clin. Res. 28:267-270. Kelley, W.N. 1985. Personnel needs for clinical research: role of the clinical investigator. Clin. Res. 33:100-104.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Kelley, W.N. 1988. Are we about to enter the golden era of clinical investigation? J. Lab. Clin. Med. 111:365-370. Kelley, W.N. 1992. Primary care and subspecialty medicine. Fostering a unified internal medicine. J. Gen. Intern. Med. 7:221-224. Kelley, W.N. and J.K. Stross. 1992. Faculty tracks and academic success. Ann. Intern. Med. 116:645-659. Kennedy, T.J. 1990. The rising cost of NIH-funded biomedical research. Acad. Med. 65:63-73. Kimes, B.W., V. Cairoli, E.J. Freireich, J. Carp, and S.S. Yang. 1991. Training in clinical research in oncology. Cancer Res. 51:753-756. Krimsky, S., J.G. Ennis, and R. Weissman. 1991. Academic-corporate ties in biotechnology: A quantitative study. Sci. Tech. Hum. Values 16:275-287. Kyle, W.C. 1984. What became of the curriculum development projects of the 1960s? How effective were they? What did we learn from them that will help teachers in today's classrooms? In Research Within Reach: Science Education. D. Holdzkiom and P.B. Lutz, eds. Charlestown, W.V.: Appalachia Educational Laboratory. Laetz, T., and G. Silverman. 1991. Reimbursement policies constrain the practice of oncology. J. Am. Med. Assoc. 266:2996-2999. Lapoint, A.E., N.A. Mead, and G.W. Phillips. 1989. A World of Differences: An International Assessment of Mathematics and Science. Princeton, N.J.: Educational Testing Service. Leaf, A. 1989. Cost-effectiveness as a criterion for Medicare coverage. N. Engl. J. Med. 321:898-900. Lederman, L.M. 1991. Science: The end of the frontier. Science 251(Suppl.) Ledley, F.D. 1991. The physician-scientist's role in medical research and the mythology of intellectual tradition. Perspect. Biol. Med. 34:410-420. Lee, T., and L. Goldman. 1994. Models of postdoctoral training for clinical research. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Lee, T.H., F.P. Ognibene, and J.S. Schwartz. 1991. Correlates of external research support among respondents to the 1990 American Federation for Clinical Research survey. Clin. Res. 39:135-144. Levey, B.A., N.O. Gentile, P. Jolly, H.N. Beaty, and G.S. Levey. 1990. Comparing research activities of women and men faculty in departments of internal medicine. Acad. Med. 65:102-106. Levey, G.S., C.R. Sherman, N.O. Gentile, and L.J. Hough. 1988. Postdoctoral research training of full-time faculty in academic departments of medicine. Ann. Intern. Med. 109:414-418. Levinson, W., S. Tolle, and C. Lewis. 1989. Women in medicine: Combining career and family . N. Engl. J. Med. 321:1511-1517. Levinson, W., and J. Weiner. 1991. Promotion and tenure of women and minorities on medical school faculties. Ann. Intern. Med. 114:63-67. Liaison Committee on Medical Education (LCME). 1991. Functions and Structure of a Medical School. Washington, D.C.: Association of American Medical Colleges and American Medical Association. Littlefield, J.W. 1984. On the difficulty of combining basic research with patient care. Am. J. Hum. Genet. 36:731-735. Littlefield, J.W. 1986. The need to promote careers that combine research and clinical care. J. Med.Educ. 61:785-789.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Lockheed, M.E., M. Thorpe, J. Brooks-Gunn, P. Casserly, and A. McAloon. 1985. Understanding sex/ethnic related differences in mathematics, science and computer science for students in grades four to eight. Princeton, N.J.: Educational Testing Service. Low, G.M. 1983. The organization of industrial relationships with universities. Pp. 68-80 in Partners in the Research Enterprise: University-Corporate Relations in Science and Technology. T.W. Langfitt, S. Hackney, A.P. Fishman, and A.V. Glowasky, eds. Philadelphia:University of Pennsylvania Press. Malcom, S.M 1983. Equity and excellence: Compatible goals. Washington, D.C.: American Association for the Advancement of Science. Malone, T.E. 1992. The moral imperative for biomedical research. Pp 3-32 in Biomedical Research: Collaboration and Conflict of Interest. R.J. Porter and T.E. Malone, eds. Baltimore:Johns Hopkins University Press. Marshall, E. 1994. Strong medicine for NIH. Science 264:896-898. Martin, J.B. 1991. Training physician-scientists for the 1990s. Acad. Med. 66:123-129. Martin, J.F., W.G. Henderson, F.R. Rickles, et al. 1984. Accrual of patients into a multihospital cancer clinical trial and its implications on planning future studies. Am. J. Clin. Oncol. 7:173-182. Massachusetts Institute of Technology (MIT). 1990. Education that works: An action plan for the education of minorities. Cambridge, Mass.: MIT Press Matyas, M.L. 1994. Early Exposure to Research: Opportunities and Effects. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research . Washington, D.C. Matyas, M.L., and S.M. Malcom, eds. 1991. Investing in the Human Potential: Science and Engineering at the Crossroads. Washington, D.C.: American Association for the Advancement of Science. McClellan, D.A., and P. Talalay. 1992. M.D.-Ph.D. training at The Johns Hopkins University School of Medicine, 1962-1991. Acad. Med. 67:36-41. McManus, I.C. 1991. How Will Medical Education Change? Lancet 337:1519-1521. Medical Research Council. 1948. Streptomycin treatment of pulmonary tuberculosis. Br. Med. J. 2:769-783. Menkes, J.H. 1981. The physician-scientist: Past, present and future. Johns Hopkins Med. J. 148:175-178. Merton, R.K. 1942. Science and technology in a democratic order. J. Leg. Polit. Sci. 1:15-26. Meyer, C.T., and A. Price. 1992. The crisis in osteopathic medicine. Acad. Med. 67:810-816. Moertel, C.G. 1991. Off-label drug use for cancer therapy and national health care priorities. J. Am. Med. Assoc. 266:3031-3032. Moody, F.G. 1992. The changing health care economy: Impact on surgical techniques. In Medical Innovation at the Crossroads, volume 2. Technology and Health Care in an Era of Limits. A.C. Geligns, ed. Washington, D.C.:National Academy Press. Movsesian, M.A. 1990. Effect on physician-scientists of the low funding rate of NIH grant applications. N. Engl. J. Med. 322:1602-1604. Nathan, D.G. 1987. Sounding Board: Funding subspecialty training for clinical investigators. N. Engl. J. Med. 316:1020-1022.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Nathan, D.G. 1988. Training in Clinical Investigation. In Resources for Clinical Investigation. Institute of Medicine. Washington, D.C.: National Academy Press. National Academy of Sciences (NAS), Government-University-Industry Research Roundtable. 1986. New Alliances and Partnerships in American Science and Engineering. Washington, D.C.: National Academy Press. National Academy of Sciences (NAS), Government-University-Industry Research Roundtable. 1987. Nurturing Science and Engineering Talent: A Discussion Paper. Washington, D.C.: National Academy Press. National Academy of Sciences (NAS), Government-University-Industry Research Roundtable. 1991. Industrial Perspectives on Innovation and Interactions with Universities. Washington, D.C.: National Academy Press. National Academy of Sciences (NAS), Government-University-Industry Research Roundtable. 1992. Fateful Choices: The Future of the U.S. Academic Research Enterprise. Washington, D.C.: National Academy Press. National Institutes of Health (NIH). 1986. Review of the Mission of the Clinical Center. D.W. Seldin, panel chair. Bethesda, Md. National Institutes of Health (NIH). 1989a. Review of the National Institutes of Health Biomedical Research Training Programs. Bethesda, Md. National Institutes of Health (NIH). 1989b. Biomedical Research: The Next Generation of Scientists. Proceedings of the 59th Meeting of the Advisory Committee to the Director, National Institutes of Health. Bethesda, Md. National Institutes of Health (NIH). 1992a. Clinical Trials Report: FY 1988-FY 1989. Office of Medical Application of Research. Bethesda, Md. National Institutes of Health (NIH). 1992b. DRG Peer Review Trends; Member Characteristics: DGR Study Sections, Institute Review Groups, Advisory Councils and Boards, 1981-1991. Bethesda, Md.: National Institutes of Health. National Institutes of Health (NIH). 1992c. NIH Data Book 1992. Bethesda, Md. National Institutes of Health (NIH). 1992d. Summary report of meeting of Dr. Bernadine Healy, Director, National Institutes of Health, with Chairpersons of NIH Initial Review Groups. Bethesda, Md. National Research Council (NRC). 1987a. Minorities: Their Underrepresentation and Career Differentials in Science and Engineering. Proceedings of a Workshop. Washington, D.C.: National Academy Press. National Research Council (NRC). 1987b. Women: Their Underrepresentation and Career Differentials in Science and Engineering (Proceedings of a Workshop). Washington, D.C.: National Academy Press. National Research Council (NRC). 1989a. Biomedical and Behavioral Research Scientists: Their Training and Supply, Volume 1, Findings. Washington, D.C.: National Academy Press. National Research Council (NRC). 1989b. Everybody Counts: A Report to the Nation on the Future of Mathematics Education. Washington, D.C.: National Academy Press. National Research Council (NRC). 1990. Fullfilling the Promise: Biology in the Nation's Schools. Committee on High School Biology. Washington, D.C.: National Academy Press. National Research Council (NRC). 1991. Women in Science and Engineering: Increasing Their Numbers in the 1990s. Washington, D.C.: National Academy Press.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities National Science Board (NSB). 1981. University-Industry Research Relationships: Myths, Realities and Potentials. Fourteenth Annual Report of the National Science Board. Washington, D.C.: National Science Foundation. National Science Board (NSB). 1991. Science and Engineering Indicators. NSB 91-1. Washington, D.C.: National Science Foundation. National Science Foundation (NSF). 1987a. Report on Funding Trends and Balance of Activities: National Science Foundation 1951-1988. NSF 88-3. Washington, D.C. National Science Foundation (NSF). 1987b. Biotechnology Research and Development Activities in Industry: 1984 and 1985. NSF 87-311. Washington, D.C. National Science Foundation (NSF). 1988a. The Science and Technology Resources of Japan: A Comparison with the United States. NSF 88-318. Washington, D.C. National Science Foundation (NSF). 1988b. Science Resource Highlights: Industrial Biotechnology R&D Increased an Estimated 12 Percent in 1987 to $1.4 Billion. NSF 88-306. Washington, D.C. National Science Foundation (NSF). 1989. Science and Technology Resources: Funding and Personnel. NSF 89-300. Washington, D.C. National Science Foundation (NSF). 1990. Women and Minorities in Science and Engineering. NSF 90-301. Washington, D.C. National Science Foundation (NSF). 1992. America's Academic Future: A Report of the Presidential Young Investigator Colloquium on U.S. Engineering, Mathematics, and Science Education for the Year 2010 and Beyond. NSF 91-150. Washington, D.C. Neinstein, L.S., and R.G. Mackenzie. 1989. Prior training and recommendations for future training of clinical research faculty members. Acad. Med. 64:32-35. Neufeld, V.R., C.A. Woodward, and S.M. MacLoed. 1989. The McMaster M.D. program: A case study of renewal in medical education. Acad. Med. 64:423-432. Newcomer, L.N. 1990. Defining experimental therapy--a third-party payer's dilemma. N. Engl. J. Med. 323:1702-1704. Nickerson, K.G., N.M. Bennett, D. Estes, and S. Shea. 1992. The status of women at one academic medical center: Breaking through the glass ceiling. J. Am. Med. Assoc. 264:1813-1817. Oates, J.A. 1982. Presidential Address: Clinical investigation: A pathway to discovery. Trans. Assoc. Am. Physicians 95:1xxviii-xc. Orthopaedic Research and Education Foundation. 1991. Defining the Current Status of Orthopaedic Research: Scope, Funding, Personnel, Facilities and Areas of Study. Chicago, Il.: Council on Research, American Academy of Orthopaedic Surgeons. Osborne, E.H.S., V.L. Ernster, and J.B. Martin. 1992. Women's attitudes toward careers in academic medicine at the University of California, San Francisco. Acad. Med. 67:59-62. Paiva, R.E., C. Donnelly, H.B. Haley, et al. 1975. Factors Related to Medical Students' Research Activities . J. Med. Educ. 50:339-345. Pak, C. 1994. Role of the GCRC in Establishing Career Paths in Clinical Research. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Parris, M., and E.J. Stemmler. 1984. Development of clinician-educator faculty track at the University of Pennsylvania. J. Med. Educ. 59:465-470.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Peck, C. 1988. Training of Clinical Investigators. In Resources for Clinical Investigation. Institute of Medicine. Washington, D.C.: National Academy Press. Penchansky, R., J.R. Landis, and M.B. Brown. 1988. Education for clinical research: An experiment at the University of Michigan. Clin. Res. 36:21-32. Pharmaceutical Manufacturers Association. 1989. Annual Survey Report of the U.S. Pharmaceutical Industry, 1987-1989. Washington, D.C. Piccirillo, J.F. 1992. The Robert Wood Johnson Scholars Program: A research training plan. Otolaryngol. Head Neck Surg. 106:25-26. Pion, G. 1994. The effectiveness of federally supported research training in preparing clinical investigators: Important questions but few answers . Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Pool, R. 1991. The social return of academic research. Nature, 352:661. Porter, R.J. 1992. Conflicts of interest in research: The fundamentals. Pp. 121-134 in Biomedical Research: Collaboration and Conflict of Interest. R.J. Porter, and T.E. Malone, eds. Baltimore, Md:Johns Hopkins University Press. President's Council of Advisors on Science and Technology. 1992. Renewing the Promise: Research-Intensive Universities and the Nation. Washington, D.C.: White House Office of Science and Technology Policy. Price, F.D. 1985. Industry and academia in collaboration: The Pfizer experience. Circulation 72(Suppl. I):13-17. Prystowsky, J.H. 1992. Factors influencing the pursuit of careers in academic medicine: A survey of M.D.-Ph.D. residents in dermatology programs in the United States. J. Invest. Dermatol. 98:125-127. Quantum Research Corporation. 1991. Prospective and retrospective trainee analysis. Developed for the Planning and Policy Research Branch, Office of Science Policy and Legisation, National Institutes of Health. Bethesda, Md. Rahimtoola, S.H. 1990. The sad plight of the clinician-clinical investigator: "Don't boil the frog in the pot." Circulation 81:1702-1706. Raskin, I. 1992. Research Funding at the Agency for Health Care Policy and Research. Presentation at the IOM workshop on Clinical Research and Training: Spotlight on Funding. Washington, D.C. Reigelman, R.K, G.J. Povar, and J.E. Ott. 1983. Medical student's skills, attitudes, and behavior needed for literature reading. J. Med. Educ. 58:411-417. Robert Wood Johnson Foundation. 1987. Special Report: The Foundation's Minority Medical Training Programs. Number 1. Princeton, N.J. Roper, W.L., W. Winkenwerder, G.M. Hackbarth, and H. Krakauer. 1988. Effectiveness in health care: An initiative to evaluate and improve medical practice. N. Engl. J. Med. 319:1197-1202. Ross, R.S. 1985. Boundaries of the General Clinical Research Center in an academic medical center. Clin. Res. 33:105-110. Sackett, D.L., R.B. Haynes, and P. Tugwell. 1985. Clinical Epidemiology: A Basic Science for clinical Medicine. Boston: Little Brown. Sadeghi-Nejad, A.B., and M.M. Marquardt. 1991. Academic physicians: Today's dinosaurs? Am. J. Med. 90:371-373. Safran, D.B., H.D. Crombie, L. Allen, et al. 1992. Preliminary assessment of a scientific curriculum in a surgical residency program. Arch. Surg. 127:529-535. Schaller, J.G. 1990. The advancement of women in academic medicine. J. Am. Med. Assoc. 264:1854-1855.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Science Services, Inc. 1991. 1992 Directory of Student Science Training Programs for Precollege Students. Washington, D.C. Segal, S., T. Lloyd, P.S. Houts, et al. 1990. The association between students' research involvement in medical school and their postgraduate medical activities. Acad. Med. 65:530-533. Seggel, R.L. 1985. Stabilizing the Funding of NIH and ADAMHA Research Project Grants. Washington, D.C.: National Academy Press. Selker, L. 1994. Clinical Research in Allied Health. In Career Paths for Clinical Research, Volume 2. Institute of Medicine. Washington, D.C.: National Academy Press. Shapley, W.H. 1992. The Budget Process and R&D. New York: Carnegie Commission on Science, Technology, and Government. Shaw, L. 1992. A misunderstood specialty: A survey of physicians in the pharmaceutical industry. J. Clin. Pharmacol. 31:419-422. Sherman, C.R. 1983. Notes on the NIH Role in Support of Postdoctoral Research Training of Two Groups of Physicians. Bethesda, Md.: National Institutes of Health. Sherman, C.R. 1989. The NIH Role in the Training of Individual Physician Faculty: A Supplementary Analysis. Bethesda, Md.: National Institutes of Health. Sherman, C.R., H.P. Jolly, T.E. Morgan, et al. 1981. On the Status of Medical School Faculty and Clinical Research Manpower, 1986-1990. Bethesda, Md.: National Institutes of Health. Shipp, A. 1992. How to control conflict of interest. Pp. 163-184 in Biomedical Research: Collaboration and Conflict of Interest. R. Porter and T.E. Malone, eds. Baltimore, Md.: Johns Hopkins University Press. Shulkin, D.J., J.J. Escarci, C. Enarson, and J.M. Eisenberg. 1991. Impact of the Medicare fee schedule on an academic department of medicine. J. Am. Med. Assoc. 266:3000-3003. Shuster, A.L., L.E. Cluff, M.A. Haynes, et al. 1983. An innovation in physician training: The Clinical Scholars Program. J. Med. Educ. 58:101-111. Smith, D.B. 1992. The future of research at the Department of Veterans Affairs. Acad. Med. 67:836-837. Smith, D.B. 1992b. Research Funding in the Department of Veterans Affairs. Presentation at the IOM Workshop on Clinical Research and Training: Spotlight on Funding. Washington, D.C. Smith, L.H. 1989. Training of physician/scientists in biomedical and behavioral research: Their training and supply. In Biomedical and Behavioral Scientists: Their Training and Supply. National Research Council. Washington, D.C.: National Academy Press. Smith, R. 1988. Medical researchers: Training and straining. Br. Med. J. 296:920-924. Smith, W.C.J. 1992. Report on medical school faculty salaries 1991-1992. Washington, D.C.: Association of American Medical Colleges. Spilker, B. 1992. Career opportunities for physicians in the pharmaceutical industry. J. Clin. Pharmacol. 29:1069-1076. Stolley, P. 1988. The training of clinical investigators. In Resources for Clinical Investigation. Institute of Medicine. Washington, D.C.: National Academy Press. Stossel, T.P., and S.C. Stossel. 1990. Declining American representation in leading clinical research journals. N. Engl. J. Med. 322:739-742.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Strickland, S.P. 1972. Politics, Science, and Dread Disease: A Short History of United States Medical Research Policy. Cambridge, Mass.: Harvard University Press. Swazey, J.P. 1994. Advisers, mentors, and role models in graduate and professional education: Implications for the recruitment, training, and retention of physician-investigators. Background paper for the Institute of Medicine Committee on Career Paths for Clinical Research. Washington, D.C. Telling, F.W. 1992. Managed care and pharmaceutical innovation. In Medical Innovation at the Crossroads, Volume 3. Technology and Health Care in an Era of Limits. A.C. Geligns, ed. Washington, D.C.: National Academy Press. Thacker, S.B., R.A. Goodman, and R.C. Dicker. 1990. Training and service in public health practice, 1951-90--CDC's Epidemic Intelligence Service. Public Health Rep. 106:599-604. Thier, S.O. 1980. Clinical investigation in the 1980s: Perspective of the medical schools. Clin. Res. 28:248-251. Thier, S.O., D.R. Challoner, J. Cockerham, et al. 1980. Proposals addressing the decline in the training of physician-investigators: report of the ad hoc committee of the AAMC. Clin. Res. 28:85-93. Tobias, S. They're Not Dumb, They're Different: Stalking the Second Tier. Tuscon, Ariz.: Research Corporation. Tudor, C.G., and D.W. Lindley, eds. 1988. Trends in Medical School Applicants and Matriculants--1978-1987. Washington, D.C.: Association of American Medical Colleges. U.S. Congress. 1993. National Institutes of Health Revitalization Act of 1993. Public Law 103-43. Washington, D.C.: U.S. Government Printing Office. U.S. Congress, Office of Technology Assessment. 1984. Commercial Biotechnology: An International Analysis. OTA-BA-218. Washington, D.C.: U.S. Government Printing Office. U.S. Congress, Office of Technology Assessment. 1985. Demographic Trends and the Scientific and Engineering Workforce. OTA-TM-SET-35. Washington, D.C.: U.S. Government Printing Office. U.S. Congress, Office of Technology Assessment. 1988a. Educating Scientists and Engineers: Grade School to Grad School. OTA-SET-377. Washington, D.C.: U.S. Government Printing Office. U.S. Congress, Office of Technology Assessment. 1988b. New Developments in Biotechnology: U.S. Investment in Biotechnology--Special Report. OTA-BA-360. Washington, D.C.: U.S. Government Printing Office. U.S. Congress, Office of Technology Assessment. 1990. Proposal Pressure in the 1980s: An Indicator of Stress on the Federal Research System. A staff paper. Washington, D.C.: OTA. U.S. Congress, Office of Technology Assessment. 1991. Federally Funded Research: Decisions for a Decade. OTA-SET-490. Washington, D.C.: U.S. Government Printing Office. U.S. Department of Commerce, Bureau of the Census. 1983. Projections of the Population of the United States by Age, Sex, and Race, 1983 to 2080. Current Population Reports Series P-25, No. 925. Washington, D.C. U.S. Department of Education, Office of Educational Research and Improvement. 1991. The Condition of Education, 1991: Postsecondary Education, Volume 2. NCES 91-637. Washington, D.C.: National Center for Education Statistics.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities U.S. Department of Education, Office of Special Education and Rehabilitative Services. 1991. NIDRR Program Directory: Fiscal Year 1991. Silver Spring, Md: National Rehabilitation Information Center. U.S. Department of Health, Education, and Welfare. 1958. Secretary's Consultants Report: Advancement of Medical Research and Education. Washington, D.C.: U.S. Department of Health, Education, and Welfare, Public Health Service. 1976. Report of the President's Biomedical Research Panel. DHEW Publication No. (OS) 76-500. Washington, D.C. U.S. Department of Health and Human Services, Food and Drug Administration; Center for Drug Evaluation and Research. 1992. Office of Professional Development and Staff College Catalog. Publication No. HFD-3. Rockville, Md. U.S. Department of Health and Human Services, Public Health Service. 1985. DRG Peer Review Trends, Workload and Actions of DRG Study Sections, 1975-1985. Bethesda, Md.: National Institutes of Health. U.S. Department of Health and Human Services, Public Health Service. 1989. ADAMHA Data Source Book FY 1988. ADAMHA Program Analysis Report No. 89-18. Rockville, Md.: Alcohol, Drug Abuse, and Mental Health Administration. U.S. Department of Health and Human Services, Public Health Service. 1991a. General Clinical Research Centers. Publication No. 91-1433. Bethesda, Md.: National Institutes of Health. U.S. Department of Health and Human Services, Public Health Service. 1991b. Report to Congress: Progress of Research on Outcomes of Health Care Services and Procedures. Publication No. 91-0004. Bethesda, Md.: Agency for Health Care Policy and Research. U.S. Department of Health and Human Services, Public Health Service. 1991c. A Research Agenda for Primary Care: Summary of a Conference. Publication No. AHCPR 91-08. Bethesda, Md: Agency for Health Care Policy and Research. U.S. Department of Health and Human Services, Public Health Service. 1991d. Primary Care Research: Theory and Methods: AHCPR Conference Proceedings. Publication No. AHCPR 91-0011. Bethesda, MD: Agency for Health Care Policy and Research. U.S. Department of Health and Human Services, Public Health Service. 1991e. NIH Almanac. Publication No. 91-5. Bethesda, Md.: National Institutes of Health. U.S. Department of Health and Human Services, Public Health Service. 1992a. Extramural Trends, FY 1982-91. Bethesda, Md.: National Institutes of Health, Division of Research Grants. U.S. Department of Health and Human Services, Public Health Service. 1992b. NIH Advisory Committees: Authority, Structure, Function, Members. Publication No. 92-11. Bethesda, Md.: National Institutes of Health. U.S. Department of Health and Human Services, Public Health Service. 1992c. NIH Data Book 1992. National Institutes of Health Publication No. 92-1261. Bethesda, Md. U.S. Department of Health and Human Services, Public Health Service. 1992d. National Institutes of Health Loan Repayment Program for AIDS Researchers, Applicant Information Bulletin, 1992 Fiscal Year. Bethesda, Md.: National Institutes of Health. U.S. Department of Veterans Affairs. 1991. Final Report of the Department of Veterans Affairs Advisory Committee for Health Research Policy: January 1990-January 1991. Washington, D.C.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities U.S. General Accounting Office. 1988. Biomedical Research: Issues Related to Increasing Size of NIH Grant Awards. Report No. GAO/HRD-88-90BR. U.S. General Accounting Office. 1991. Off-Label Drugs: Reimbursement Policies Constrain Physicians in their Choice of Cancer Therapies. No. GAO/PEMD-91-14. Washington, D.C. U.S. General Accounting Office. 1992a. Cross-Design Synthesis--A New Strategy for Medical Effectiveness Research. No. GAO/PEMD-92-18. Washington, D.C. U.S. General Accounting Office. 1992b. Controlling Inappropriate Access to Federally Funded Research Results. Publication No. RCED-92-104. Washington, D.C. U.S. House of Representatives, Committee on Science, Space, and Technology. 1992. Report of the Task Force on the Health of Research. Washington, D.C.: U.S. Government Printing Office. Vaitukaitis, J.L. 1991. The future of clinical research. Clin. Res. 39:145-156. Vance, C. 1982. The mentor connection. J. Nurs. Admin. 38:7-13. Varrin, R.D., and D.S. Kukich. 1985. Guidelines for industry-sponsored research at universities. Science 227:385-388. Waugaman, P.G., and R.J. Porter. 1992. Mechanisms of interaction between industry and the academic medical center. Pp. 93-118 in Biomedical Research: Collaboration and Conflict of Interest. R.J. Porter and T.E. Malone, eds. Baltimore, Md.: Johns Hopkins University Press. Weiss, I.R. 1987. Report of the National Survey of Science and Mathematical Education. Research Triangle Park, N.C.: Research Triangle Institute. Weiss, I.R., B.H. Nelson, S.E. Boyd, and S.B. Hudson. 1989. Science and Mathematics Education Briefing Book. Washington, D.C.: National Science Teachers Association. Wennberg, J.E. 1990. What is outcomes research? In Medical Innovation at the Crossroads, Volume 1. Modern Methods of Clinical Investigation. A.C. Geligns, ed. Washington, D.C.: National Academy Press. Wennberg, J.E., K. McPhearson, and P. Caper. 1984. Will payment based on diagnosis-related groups control hospital costs? N. Engl. J. Med. 311:295-300. Wennberg, J.E., A.G. Mulley, Jr., D. Hanley, R.P. Timothy, F.J. Fowler, Jr., N.P. Roos, M.J. Barry, K. McPherson, E.R. Greenberg, D. Soule, et al. 1988. An assessment of prostatectomy for benign urinary tract obstruction. Geographic variations and the evaluation of medical care outcomes. J. Am. Med. Assoc. 259:3027-30. White House Science Council. 1986. A Renewed Partnership. Washington, D.C.: White House Office of Science and Technology Policy. Whybrow, P.C. 1988. Clinical research training in psychopharmacology--context and climate: Notes from the chairman's perspective. Psychopharmacol. Bull. 24:285-287. Witt, M.D., ed. 1991. Industry/University/Government Biomedical Research Alliances in the Public Interest: Models for the Future. Adapted from a Symposium at the Forsythe Dental Center, Boston, MA. Washington, D.C.: The Journal of NIH Research. Wittes, R.E. 1987a. Antineoplastic agents and FDA regulations: Square pegs for round holes? Cancer Treatment Rep. 71:795-806. Wittes, R.E. 1987b. Paying for patient care in treatment research--who is responsible? Cancer Treatment Rep. 71:107-113. Wittes, R.E. 1988. From research to approved treatment: Overcoming the obstacles. Semin. Oncol. 25:38-42.

OCR for page 219
Careers in Clinical Research: Obstacles and Opportunities Woods, D. 1979. Can students and practicing doctors be encouraged to do medical research, and should they? Can. Med. Assoc. J. 121:352-355. Wyngaarden, J.B. 1979. The clinical investigator as an endangered species. N. Engl. J. Med. 301:1254-1259. Wyngaarden, J.B. 1983. Encouraging young physicians to pursue a career in clinical research. Clin. Res. 31:115-118. Wyngaarden, J.B. 1986. The priority of patient-oriented research. Clin. Res. 33:95-104.

OCR for page 219
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