undergraduate and medical degrees from Emory University in Atlanta and training in internal medicine, rheumatology and genetics at the University of Texas Southwestern Medical School and Parkland Memorial Hospital in Dallas, the Massachusetts General Hospital and Harvard Medical School in Boston, and the National Institutes of Health in Bethesda, where he received the John D. Lane Award of the U.S. Public Health Service for his research contributions. Dr. Kelley's bibliography lists in excess of 240 publications and 12 books, and he has participated as a member of the editorial boards of 12 medical journals. He is the founder and senior editor of The Textbook of Rheumatology, which is now in its 4th edition, and is the founder and editor-in-chief of The Textbook of Internal Medicine.

KAREN H. ANTMAN, M.D., is Professor of Medicine and Chief of the Division of Medical Oncology at Columbia-Presbyterian Medical Center. Dr. Antman received her M.D. from the College of Physicians & Surgeons of Columbia University and joined the Harvard Medical School faculty in 1979. She previously was Associate Professor at the Harvard Medical School, where she was Clinical Director of the Dana Farber Cancer Institute and Beth Israel Hospital Solid Tumor Autologous Marrow Program and coordinated the sarcoma and mesothelioma clinical research and treatment programs at the Dana Farber Cancer Institute. Dr. Antman moved to Columbia-Presbyterian Medical Center in 1993. She has published extensively on bone marrow transplantation, hematopoietic cytokines, and sarcomas and mesotheliomas, and is coeditor of two textbooks, Asbestos Related Malignancy and High Dose Cancer Therapy. The latter examines the state of the art of bone marrow transplantation, hematopoietic stem cells and hematopoietic cytokines. The solid tumor marrow transplant program under her direction initially began pilot trials of new regimens in incurable breast cancer and other solid tumors on the basis of laboratory-based observations and has expanded to randomized trials with significantly less toxic regimens with curative intent. She has consulted for the U.S. Department of Justice on asbestos-related malignancies and served on the Health and Human Services Advisory Board Study of Coverage of Investigational Therapy, on the Physicians Payment Review Commission/American Medical Association Consensus Panel for Evaluation and Management of Services, and on the Harvard Resource Based Relative Value Scale Technical Consulting Panel. She is currently an associate editor of Cancer Research, is on the editorial board of Annals of Internal Medicine and the New England Journal of Medicine, and is president of the American Society for Clinical Oncology.

DOROTHY BROOTEN, Ph.D., R.N., is the Director of the Center for Low Birthweight: Prevention and Care, Professor in the Health Care of Women and Childbearing Division at the University of Pennsylvania School of Nursing, and the Overseers Term Chair in Perinatal Research. She is a member of the

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