Antiglucocorticoid effects, 1, 13, 16, 52, 55, 76, 78, 104-105, 140 -141, 234-239, 244

of cancer therapy, 10, 21, 40, 41, 236

of endometriosis therapy, 9, 38, 39

of low dosages, 4, 9, 21

research needs, 13, 55, 239-240

therapeutic, 13, 53-55, 170, 234-235, 239-240, 271

Antihormone antibodies, 73

Antitumor effects, 11, 43-44, 47, 103-104, 106, 217-219, 235-236

Apoptosis, and breast cancer therapy, 12, 43, 103

Arthritis, 55, 236

Azastene, 258

B

Biosynthesis inhibition, 73, 257-259

Bone retention and loss, 4, 10, 21, 22, 38, 40

Brain, see Meningiomas;

Mood effects

Breast cancer, 11, 41-47, 91, 103-104, 105, 210, 271

animal studies, 11, 43-44, 47, 60, 217-219

dosages, 12, 46, 48

and oral contraceptives, 20

progesterone receptors, 11, 12, 42-43, 48, 123-124, 133, 213-217, 220-222

research needs, 11-12, 47-48, 222-224

and side effects, 12, 45

C

Cancer and tumors, see Antitumor effects;

Breast cancer;

Meningiomas;

Uterine leiomyomas

Cardiovascular effects, of prostaglandin, 27-28, 94, 167

Cataracts, 55, 236

Cervical mucus, 139-140, 141

Cervical ripening, 7-8, 32-33, 96-97, 165, 270

for abortion, 32, 96-97, 175, 177-179, 270

dosages, 32, 177-178

side effects, 32

Cesarean section, 34

Chemoprevention, for breast cancer, 11, 45-46

China, abortifacient use and licensing, 149, 271

trials, 265

Cholesterol, 140

Chromatin modification, 88

Clinical trials, 2-3, 18

abortifacient use, 6, 7, 29, 31-32, 165, 166-167, 168-170, 176

breast cancer therapy, 11-12, 44-45, 47-48, 60, 103, 219-220, 223

cervical ripening, 177-179

contraceptive use, 4, 22, 160

endometriosis therapy, 10, 38-39, 189, 190, 192-197

leiomyoma therapy, 10, 189-190, 198-207

meningioma therapy, 13, 49, 50

post-coital contraception, 5, 23, 160

Complications, see Antiglucocorticoid effects;

Side effects and toxicity

Conception, 19

Contraception, definition, 72, 98.

See also Contraceptive use;

Menses induction;

Oral



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