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The Children's Vaccine Initiative: Achieving the Vision (1993)
Institute of Medicine (IOM)

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. "4 Vaccine Demand and Supply." The Children's Vaccine Initiative: Achieving the Vision. Washington, DC: The National Academies Press, 1993.

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The Children's Vaccine Initiative: Achieving the Vision

Product and Company

Development Status

Diphtheria and tetanus toxoids and pertussis vaccine, Haemophilus influenzae type b, hepatitis B vaccine

Phase I (by summer of 1993)

Merck & Co., Inc./Connaught Laboratories, Inc.

 

Diphtheria and tetanus toxoids and pertussis vaccine, Haemophilus influenzae type b, hepatitis B vaccine and inactivated polio vaccine

Phase I (by summer of 1993)

Merck & Co., Inc./Connaught Laboratories, Inc.

 

Diphtheria and tetanus toxoids and pertussis vaccine, hepatitis B and Haemophilus influenzae type b conjugate vaccine

Pre-clinical studies completed; preparing IND submissions

Michigan Department of Public Health/ SmithKline Beecham

 

Diphtheria and tetanus toxoids and acellular pertussis vaccine and hepatitis B vaccine and Haemophilus influenzae type b conjugate vaccine

Pre-clinical studies completed; preparing IND submissions

Michigan Department of Public Health/ SmithKline Beecham

 

Diptheria and tetanus toxoids and pertussis vaccine, adsorbed, and poliovirus vaccine, inactivated

PLA submitted

Connaught Laboratory, Inc./Pasteur Mérieux Sérums et Vaccins

 

Act HIBTM Haemophilus influenzae type b conjugate vaccine (tetanus protein conjugate)

PLA submitted

Connaught Laboratories, Inc./Pasteur Mérieus Sérums et Vaccins

 

Haemophilus influenzae type b conjugate vaccine

Phase III

Massachusetts Department of Public Health

 

Haemophilus influenzae type b conjugate vaccine, hepatitis B vaccine

Phase Ill

Merck & Co., Inc.

 

VAQTATM hepatitis A vaccine

Phase III

Merck & Co., Inc.

 

Hepatitis B vaccine

Phase II

Connaught Laboratories. Inc.

 

Hepatitis B vaccine

Phase III

Amgen/Johnson & Johnson

 

Herpes vaccine

Phase I (adults)

Lederle-Praxis Biologicals

 

PrymeTM lyme disease vaccine (recombinant OspA lipoprotein for Lyme borreliosis)

Phase I

Connaught Laboratories, Inc.

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