Product and Company

Development Status

Lyme disease vaccine (recombinant OspA lipoprotein for Lyme borreliosis)

Phase I (by summer of 1993)

SmithKline Beecham

 

M-M-R®II measles, mumps, rubella, and varicella

Phase III

Merck & Co., Inc.

 

Measles, mumps, rubella virus vaccine, live

Project currently inactive

Connaught Laboratories, Inc./Pasteur Mérieux Sérums et Vaccins

 

Meningococcal group B vaccine (outer membrane protein)

Phase III for 2 years of age and older

Connaught Laboratories, Inc.

 

Pneumococcal conjugate vaccine (streptococcal conjugate vaccine, diphtheria toxoid and tetanus protein conjugates for otitis media and pneumonia)

Phase I

Connaught Laboratories, Inc./Pasteur Mérieux Sérums el Vaccins

 

Pneumococcal conjugate vaccine, streptococcal pneumonia vaccine, enhanced

Phase I/II

Lederle-Praxis Biologicals

 

Pneumococcal conjugate vaccine

Phase II

Merck & Co., Inc.

 

Respiratory syncytial virus vaccine

Phase I/II

Lederle-Praxis Biologicals

 

Rhesus rotavirus vaccine

Phase III

Wyeth-Ayerst

 

Rhesus rotavirus vaccine

Phase II

Merck & Co., Inc.

 

Sabin IPV inactivated Sabin polio vaccine

Phase III (age 2 months and up)

Lederle-Praxis Biologicals

 

Salmonella, live attenuated

Phase I

Lederle-Praxis Biologicals

 

Streptococcal group B vaccine

Phase I

North American Vaccine

 

Varivax® varicella vaccine

PLA submitted

Merck & Co., Inc.

 

 

SOURCES: Pharmaceutical Manufacturers Association. 1990. New Medicines in Development for Children. Washington, D.C.; Pharmaceutical Manufacturers Association. 1990. Biotechnology Medicines. Washington, D.C.; Douglas Reynolds, Connaught Laboratories, Inc., October 1992; Glenna Crooks and Ronald B. Ellis, Merck & Co., Inc., May 1993; Jane Scott, Lederle-Praxis Biologicals, February 1993; George Siber, Massachusetts Biologic Laboratories, June 1993; Robert Meyers, Michigan Department of Public Health, May 1993; Dan Soland, SmithKline Beecham, June 1993.



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