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risk from women who are potential participants in clinical studies, where informed consent procedures and monitoring provide safeguards, to women in the general population may be unacceptable as a matter of social policy.

NOTES

1.  

Institute of Medicine, Issues in the Inclusion of Women in Clinical Trials, Washington, DC: National Academy of Sciences, 1991.

2.  

National Institutes of Health, Report of the National Institutes of Health: Opportunities for Research on Women's Health, U.S. Department of Health and Human Services, September 1992.

3.  

Jacqueline A. Horton (ed.), The Women's Health Data Book. Washington, DC: The Jacobs Institute of Women's Health, 1992.

4.  

Council on Ethical and Judicial Affairs of the American Medical Association, "Gender Disparities in Clinical Decision Making," JAMA 266:559–568, 1991.

5.  

National Women's Health Resource Center, Forging a Women's Health Research Agenda. Washington, DC: NWHRC, 1990.

6.  

NIH, Opportunities for Research on Women's Health; Horton (ed.), The Women's Health Data Book.

7.  

Centers for Disease Control, "Trends in Ischemic Heart Disease Mortality—United States, 1980–1988," MMWR 41:548, July 31, 1992.

8.  

NWHRC, Forging a Women's Health Research Agenda.

9.  

Centers for Disease Control, "Trends in Lung Cancer Incidence and Mortality—United States, 1980–1987," MMWR 39:875, December 7, 1990.

10.  

Horton (ed.), The Women's Health Data Book.

11.  

Susan Y. Chu, J. W. Buehler, and Ruth L. Berkelman, "Impact of the Human Immunodeficiency Virus Epidemic on Mortality in Women of Reproductive Age, United States," JAMA 264:225–229, 1990.

12.  

Jeane Ann Grisso and Katherine Watkins, "A Framework for a Women's Health Research Agenda," Journal of Women's Health 1:177–183, 1992.

13.  

Horton (ed.), The Women's Health Data Book.

14.  

Howard Minkoff, Jonathan D. Moreno, and Kathleen R. Powderly, "Fetal Protection and Women's Access to Clinical Trials," Journal of Women's Health 1:137–140, 1992.

15.  

Council Report, "Gender Disparities in Clinical Decision Making," JAMA 266:559–562, 1991.

16.  

John Z. Ayanian and Arnold M. Epstein, "Differences in the Use of Procedures Between Women and Men Hospitalized for Coronary Heart Disease," NEJM 325:221–225, 1991; Richard M. Steingart, Milton Packer, Peggy Hamm, et al., "Sex Differences in the Management of Coronary Artery Disease," NEJM 325:226–230, 1991; Charles Maynard, Paul E. Litwin, Jenny S. Martin, and Douglas Weaver, ''Gender Differences in the Treatment and Outcome of Acute Myocardial Infarction,'' Archives of Internal Medicine 152:972–976, 1992.



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