to retard and reduce diffusion, proportionally to the number of layers. However, diffusion is not prevented and the monomer tends to be kept in contact with the skin. Merely painting methylmethacrylate monomer on the skin of a sensitive subject has been shown not to cause an allergic reaction because the monomer evaporates so rapidly. However, if the monomer is applied under an exclusive or semiocclusive dressing, a reaction will ensue in the sensitive subject. Synthetic gloves are currently under development that we hope will be impervious to methylmethacrylate monomer.
1. FISHER, A.A.: Allergic Sensitization of the Skin and Oral Mucosa to Acrylic Denture Materials. J. Prosth. Dent., 6:593–602, 1956.
2. PEGUM, J.S., and MEDHURST, E.A.: Contact Dermatitis from Penetration of Rubber Gloves by Acrylic Monomer. British Med. J., 2:141–143, 1971.
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Case Study 49: Contact Dermatitis in Surgeons from Methylmethacrylate Bone Cement ."
Environmental Medicine: Integrating a Missing Element into Medical Education . Washington, DC: The National Academies Press,
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