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Mutch, Grant, Enkin, and Enkin, 1986; Simes, 1986). The means to do so exist. All that is needed is the collective will. Virtually all trials performed at major research institutions, regardless of the funding source, are subject to IRB review before implementation. The establishment of a system for registering trials at that point of review, along with a nationwide system for harvesting such information, would provide a means for sponsors and investigators alike to identify trials done or underway on the compound of interest or on related compounds. At present they are in the dark. At least with such a system they would have a vehicle for the identification of related investigations. Even if this did not lead to data sharing, it would at least have the potential of informing of hidden disasters.



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