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SUMMARY

The overall impression of the IOM committee is that these trials were ethically sound clinical research projects designed and carried out by highly competent investigators who frequently went beyond the requirements dictated by regulations or imposed by IRBs to respond to the desires and needs of their patient-subjects. Indeed, with rare exceptions, their relationships with the patient-subjects appeared to have elements of the depth and sensitivity to which good primary care physicians aspire in their relationships with their patients.



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