1. Changes in proportion of normal behavioral activity. (pp. 18–19)
    1. Recording reactions to routine husbandry events. (pp. 26, 45)
    2. Recording ability to respond to training. (pp. 40–42)
    3. Recording responses indicative of distress. (pp. 11, 13, 26)
    4. Other.
    1. The plan should discuss various elements of remediation (p. 21), including
      1. Means of documenting successful and unsuccessful attempts at remediating diagnosed animals. (pp. 12–13, 17)
      2. Protocols for followup of remediation efforts. (pp. 25–26)
      3. Steps taken to accommodate animals that do not respond to remediation. (p. 26)
      4. Establishment of end-point criteria (e.g., serious self-biter). (p. 35)
    1. The plan is considered to be effective and properly implemented if one of the following conditions is satisfied:
      1. Individual animals are judged to be in a state of well-being, or
      2. The cause of distress or atypical behavior in any animal can be shown to be derived from antecedent conditions of abnormal development, inappropriate rearing conditions, or an approved research protocol; practices are identified and implemented for the benefit of future generations of animals; and facility records exist for the presence, etiology, and remediation or accommodation of observed cases of lack of well-being.


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