Reactivity and Incompatibility

EDB reacts vigorously with alkali metals, zinc, magnesium, aluminum, caustic alkalis, strong oxidizers, and liquid ammonia. Liquid EDB will attack some forms of plastics, rubber, and coatings.

Storage and Handling

Because of its carcinogenicity, EDB should be handled using the "basic prudent practices" of Chapter 5.C, supplemented by the additional precautions for work with compounds of high chronic toxicity (Chapter 5.D). In particular, work with EDB should be conducted in a fume hood to prevent exposure by inhalation, and appropriate impermeable gloves and safety goggles should be worn to prevent skin contact. Gloves and protective clothing should be changed immediately if EDB contamination occurs. Since EDB can penetrate neoprene and other plastics, protective apparel made of these materials does not provide adequate protection from contact with EDB.


In the event of skin contact, immediately remove contaminated clothing and wash with soap and water. In case of eye contact, promptly wash with copious amounts of water for 15 min (lifting upper and lower lids occasionally) and obtain medical attention. If EDB is ingested, obtain medical attention immediately. If large amounts of this compound are inhaled, move the person to fresh air and seek medical attention at once.

Persons not wearing protective equipment and clothing should be restricted from areas of spill or leaks until cleanup has been completed. Soak up EDB with a spill pillow or absorbent material such as vermiculite or dry sand, place in an appropriate container, and dispose of properly. Evacuation and cleanup using respiratory protection may be necessary in the event of a large spill or release in a confined area.


Excess EDB and waste material containing this substance should be placed in an appropriate container, clearly labeled, and handled according to your institution's waste disposal guidelines. For more information on disposal procedures, see Chapter 7 of this volume.

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