Table C.1 Chronological Summary of Critical Events, NHF Communications,

Critical Event

NHF Communication

Knowledge Base

Risk Assessment

Clinical Option

NHF Action

July 16, 1982: CDC MMWR reports immunesuppressive disorder identified in three hemophiliac patients

July 14, 1982: Patient Alert #1 sent to NHF chapters and treatment centers

Speculation that it may be transmitted similarly to hepatitis virus by blood and blood products

Risk is minimal

No change in treatment

Dr. Aledort, NHF medical co-director to serve on PHS task force






Surveillance and reporting system being planned by CDC with NHF cooperation






''Dear Colleague" letter sent (July 19, 1982) to physicians by Dr. Aledort asking them to report any cases to state health departments and the NHF

July 16, 1982: FDA Office of Biologics holds information exchange meeting on the three cases with NHF and CDC representatives

July 19, 1982: Chapter Advisory #2 issued

Cause of disease unknown

No indication blood products are involved

No change in treatment (refers to this as a CDC recommendation)




Epidemic known by CDC in some homosexuals and recent Haitian immigrants

Risk is minimal





CDC investigating: (1) linkage between hemophiliacs and other populations; (2) whether the disease may be a virus transmitted similarly to hepatitis by blood products




The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement