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TABLE 2-1  Neurobehavioral Outcome of Prenatal Exposure in Humans or Animals

   
 

Alcohol


Methylmercury

Ionizing Radiation


Phenytoin


PCBs


Lead


Opioids


Marijuana


Tobacco

Gross neuropathology

Pos., NDR

Pos., DR

Pos., DR

NE

NE

NE

NE

Mental retardation

Pos., DR

Pos., DR

Pos., DR

NE

?

NE

NE

NE

NE

Reduced IQ scores

Pos., DR

Pos., DR

Pos., DR

Pos., NDR

Pos., NDR

Pos., DR

NE

?

Pos., DR

Hyperactivity

Pos., DR

Pos., NDR

?

NE

NE

Pos., DR

Attention deficit

Pos., DR

?

?

Pos., NDR

Pos., NDR

Developmental delays

Pos., DR

Pos., DR

Pos., NDR

Pos., DR

?

Pos., NDR

Pos., DR

Gait abnormality

Pos., DR

Pos., DR

NE

NE

NE

NE

NE

Fine/gross coordination

Pos., DR

Pos., DR

?

?

NE

NE

Sensory deficits

Pos., DR

Pos., DR

NE

Pos., NDR

NE

NE

Pos., Dr

Neonatal withdrawal

Pos., NDR

Pos., DR

?

Pos., DR

NOTE: Pos., DR = Positive findings, dose-related; Pos., NDR = positive findings, non-dose-related; ? = suspected, some reports; NE = no effects; and—= not tested, unknown.

   


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