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Appendix I BACKGROUND INFORMATION ON MEMBERS OF THE COMMITTEE ON NONOCCUPATIONAL HEALTH RI SKS OF ASBES TIFORM FIBERS LESTER BRESLOW, committee chairman, is Dean Emeritus and Professor of Public Health, School of Public Health, University of California at Los Angeles. His work has been devoted mainly to the epidemiology of chronic disease. He is a member of the Institute of Medicine and has served as an adviser on health matters to the World Health Organization and to several federal agencies. RICHARD R. BATES is Senior Staff Scientist, Health Effects Institute, Cambridge, Massachusetts. Previously, he served as Associate Commissioner for Science of the Food and Drug Administration and Assistant to the Director for Risk Assessment at the National Institute of Environmental Health Sciences. He has extensive knowledge in the fields of risk assessment and experimental pathology and has concentrated his research on chemical carcinogenesis and toxicology. Dr. Bates is a member of the American Association of Pathologists, the American Association for Cancer Research, and the Society of Toxicology. HENRIK H. BENDIXEN is Professor of Anesthesiology and Chairman of the Department of Anesthesiology at Columbia University in New York City. His research interests include respiratory failure and other aspects of intensive care medicine. In addition to serving on National Research Council committees studying shock and the toxicity of anesthetic agents, he has been a member of various committees of the National Institutes of Health. He is a past president of the Society of Critical Care Medicine and a member of the Institute of Medicine. STEPHEN L. BROWN is an independent consultant specializing in chemical risk assessment and related problems. His contributions include the development of techniques for estimating human exposure to chemicals and other biologically significant agents, application of systems analysis techniques to chemical risk assessment, and priority- setting for both testing and regulating hazardous substances. He was previously Director of the Center for Health and Environmental Research at SRI Inte rna Sac iona l . PATRICIA A. BUFFLER is Professor of Epidemiology and Associate Dean for Research at the University of Texas Health Science Center at the 332

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333 School of Public Hesith in Houston. Her research interests include occupational and environmental epidemiology, with special emphasis on cancer, pulmonary diseases, and reproductive disorders. She is past Chairman of the American Public Health Association Epidemiology Section and is current ly on the Board of Directors of the American College of Epidemiology . ARTHUR M. LANCER is an Associate Professor and the Associate Director of the Environmental Sciences Laboratory at the Mount Sinai School of Medicine. His research interests have included development of analytical techniques for microparticles, measurement and characterization of asbestos fiber in human tissues, and determination of physicochemical propert ies of mineral dusts that impart biological activity. In addition to serving on many governmental advisory committees, he has acted as consultant to the International Agency for Research on Cancer of the World Health Organization and to the Norwegian and South African governments on subjects related to asbestos exposure and health effects. JEREMIAH LYNCH is the Industrial Hygiene Manager of the Exxon Chemical Company. Mr. Lynch previously worked at the National Institute for Occupational Safety and Health of the U. S. Public Health Service, where he conducted research in asbestos measurement, exposure monitoring strategy, and engineering control technology. He is a past Chairman of the American Conference of Governmental Industrial Hygienists and is active in V.S. and international occupational health groups. JAMES A. MERCHANT is Professor in the Department of Preventive Medicine and Environmental Health and the Department of Internal Medicine at the University of Iowa. Before assuming his present position, he was Director of the Appalachian Laboratory for Occupational Safety and Health and the Division of Respiratory Disease Studies at West Virginia University. His research interests include occupational lung diseases, epidemiology, ant pulmonary medicine. RICHARD R. MONSON is Professor of Epidemiology and Director of the Occupat tonal Health Program at the Harvard School of Public Health. His research interests include mortality studies of occupational groups as well as cancer epidemiology in general. Dr. Monson serves on the National Research Council Committee on Amines. BROOKE T. MOSSMAN is Assistant Professor of Pathology at the University of Vermont College of Medicine. She conducts research on cellular mechanisms of asbestos-induced injury and disease, with particular interest in asbestos-associated carcinogenesis. Dr. Mossman has served as a consultant to the National Science Foundation, the National Cancer Institute, the Environmental Protection Agency, and the National Institute of Environmental Health Sciences.

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334 JAMES E. TROSKO is Professor of Pediatrics and Human Development and Associate Director of the Division of Human Genetics, Genetic Toxicology, Endocrinology, and Oncology in the College of Human Medicine, Michigan State University. As a molecular geneticist, Dr. Trosko's research in radiation biology at Oak Ridge National Laboratory included studier on DNA damage, DNA repair mechanisms, and In vitro mutation studies in human and other mamma tian cells. He also has conducted extensive research in chemical carcinogenesis. Currently, his research activities include both theoret ical and mechanistic studies of inn' iators and promoters of carcinogenesis. He has served on many academic, governmental, and Na~ciona1 Research Council committees and has participated in several symposia concerned with the multiple disease potentials of genotoxic and nongenotoxic agents. JOHN VAN RYZIN is Professor in the Division of Bios~catistics and Department of Statistics at Columbia University and Senior Mathematician at Brookhaven National Laboratory. His research interests include quantitative methods of risk assessment and statistical methodologies for analysis of toxicological and survival data. Dr. Van Ryzin has served an a consultant or reviewer to the Environmental Protection Agency, the Food and Drug Administration, the Office of Technology Assessment, the Nat tonal Toxicology Program, and the Food Safety Counc it . TIBOR ZOLTAI has been on the faculty of the Department of Geology and Geophysics at the University of Minnesota since 1959. His expertise lies in the areas of applied geology, mineralogy, and crystallography. Among his major scientific interests are the crystal chemistry, crystal structure and physical properties of minerals, as well as the nature and properties of asbestiform fibers.