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Xenotransplantation: Science, Ethics, and Public Policy (1996)

Chapter: Appendix A-Workshop Agenda

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Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
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A
Workshop Agenda

Xenograft Transplantation: Science, Ethics, And Public Policy

June 25-27, 1995

Bethesda Hyatt Regency Hotel—Crystal Ballroom

1 Bethesda Metro Center, Bethesda, Maryland

Sunday, June 25

9:30 a.m.

Welcome and Introduction;

Kenneth I. Shine, IOM President;

Karen Hein, IOM Executive Officer;

Norman Levinsky, Committee Chair

Session I: Assessing the Science Base

9:45

Moderator's overview of session; Keith Reemtsma

10:00

Immunology: The Early Responses; Jeffrey Platt

10:15

Immunology: The Long-Term Responses; Thomas Starzl

10:30

Issues; Olga Jonasson

10:45

Discussion

11:00

Potential Therapeutic Approaches; Moderator: Denise Faustman

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×

 

Genetic Engineering Overview; Denise Faustman

11:15

Transgenic and Knockout; Beverly Koller

11:30

Transgenic Pigs; Steven Squinto

11:45

Discussion

12:15 p.m.

LUNCH BREAK

1:00

Recipient Modification; Cellular Modification/Chimerism; Suzanne Ildstad

1:15

Nonmodification; Camillo Ricordi

1:30

Immunosuppression; Barry Kahan

1:45

Respondents and Discussion;

David K.C. Cooper

Ali Naji

2:15

Panel Status of Human Trials; Moderator: Nancy Ascher

 

David L. Cooper

Keith Reemstma

David Sharp

2:45

Discussion

3:00

BREAK

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×

Session II: Infectious Issues—Moderator: Stephen Morse

3:15

Overview; Frederick Murphy

3:45

Emerging Pathogens; Stephen Morse

4:00

Discussion

4:20

Risk Assessment; Jonathan Richmond

4:30

Infectious Risk and Risk Assessment;

Jonathan Allan

Jay A. Fishman

4:50

Discussion

5:15

Adjourn

Monday, June 26

8:30 a.m.

Specific Pathogen-Free Environments and Nonhuman Primates; Michael Keeling

8:40

Specific Pathogen-Free Environments and Swine; Michael Swindle

8:50

Panel Discussion; (all speakers)

10:15

BREAK

10:30

Applications to Humans; Moderator: Marian Michaels

11:00

Surveillance and Public Health; Louisa Chapman

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×

11:30

Detection Methods; David Persing

12:00

LUNCH BREAK

1:00 p.m.

Panel Discussion (all speakers); Respondents: Jonathan Allan, Steven Deeks

Session III: Ethics and Public Policy

Moderator: Harold Vanderpool

2:00

Social and Political Issues; Moderator: David Rothman

 

Addressing Questions Raised by Xenograft Transplantation; Renee Fox

 

Commentary and Response;

David Rothman

Stuart Youngner

2:45

Discussion

3:15

BREAK

3:30

Economics and Allocation of Organs and Tissues

 

Economic Impact of Xenograft Transplantation: Lessons from Heart Transplantation; Roger Evans

3:50

Macroeconomic Aspects of Xenograft Transplantation; Paul Menzel

4:10

Who Gets Which Organs? Questions of Justice; James Bowman

4:30

Discussion

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×

4:45

Clinical Trials Panel Discussion; Moderator: Clive Callender

 

Robert Arnold

James Bowman

Rebecca Dresser

Stuart Youngner

5:30

Discussion

5:45

Adjourn

Tuesday, June 27

8:30 a.m.

Value and Use of Animals Panel Moderator: Ralph Dell

 

Susan Leaderer

Justin Leiber

Andrew Rowan

James Walters

9:30

Discussion

9:45

Issues for Regulatory Review; Moderator: Robert Burt

 

Richard Merrill

10:15

Discussion

10:30

BREAK

10:45

The Patients' Views Panel; Moderator: John Robinson (counselor)

 

Gloria B. Liver transplant patient

Brenda L. Project Inform

Calvin W. Multiple transplant patient, and his mother, Evelyn W.

Len K. Potential kidney transplant patient

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×

11:45

Discussion

12:15 p.m.

Wrap-Up;

Norman Levinsky and Session Chairs

12:45

Adjourn

Speakers And Panelists

Jonathan Allan, D.V.M. Southwest Foundation for Biomedical Research Department of Virology and Immunology San Antonio, TX

Robert Arnold, M.D. Associate Professor of Medicine University of Pittsburgh School of Medicine Pittsburgh, PA

James Bowman, M.D. Professor Emeritus Department of Pathology, Medicine, and Committee on Genetics University of Chicago Chicago, IL

Gloria Brooks Fort Washington, MD

Louisa Chapman, M.D. Medical Epidemiologist National Center for Infectious Diseases Centers for Disease Control and Prevention Atlanta, GA

David K.C. Cooper, M.D., Ph.D. Oklahoma Transplantation Institute Baptist Medical Center of Oklahoma Oklahoma City, OK

David L. Cooper, Ph.D., M.D. Associate Professor of Pathology Department of Pathology University of Pittsburgh Pittsburgh, PA

Steven Deeks, M.D. Assistant Clinical Professor of Medicine San Francisco General Hospital San Francisco, CA

Rebecca Dresser, J.D. The Law School Case Western Reserve University Cleveland, OH

Jay A. Fishman, M.D. Chief, Clinical Transplant Infectious Disease Unit Massachusetts General Hospital Boston, MA

Suzanne Ildstad, M.D. Professor of Surgery University of Pittsburgh Pittsburgh, PA

Olga Jonasson, M.D. Director, Education and Surgical Services American College of Surgeons Chicago, Ill

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×

Barry Kahan, M.D., Ph.D. Director of Immunology and Organ Transplants University of Texas Houston, TX

Michale Keeling, D.V.M. Professor of Veterinary Medicine and Surgery University of Texas Cancer Center Bastrop, TX

Len Koch The Health, Safety and Research Alliance of New York State New York, NY

Beverly Koller, Ph.D. Department of Medicine University of North Carolina Chapel Hill, NC

Susan E. Lederer, Ph.D. Associate Professor Pennsylvania State University College of Medicine Hershey, PA

Justin Leiber, Ph.D. Professor of Philosophy Department of Philosophy University of Houston Houston, TX

Brenda Lein Project Inform San Francisco, CA

Paul T. Menzel, Ph.D. Interim Provost Pacific Lutheran University Tacoma, WA

Richard A. Merrill, L.L.B. Daniel Caplin Professor of Law University of Virginia School of Law Charlottesville, VA

Frederick Murphy, D.V.M., Ph.D. Dean, School of Veterinary Medicine University of California Davis, CA

Ali Naji, M.D. Professor of Surgery The University of Pennsylvania Philadelphia, PA

David H. Persing, M.D., Ph.D. Director Molecular Microbiology Laboratory Mayo Clinic Rochester, MN

Jeffrey L. Platt, M.D. Professor, Department of Surgery Duke University Medical Center Durham, NC

Jonathan Y. Richmond, Ph.D. Director, Office of Health and Safety Centers for Disease Control and Prevention Atlanta, GA

Camillo Ricordi, M.D. Professor of Surgery Chief, Division of Cellular Transplantation University of Miami School of Medicine Miami, FL

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×

John D. Robinson, Ed.D., MPH Chief, Interdepartmental Treatment Programs Department of Psychiatry Howard University Hospital Washington, DC

Andrew Rowan, Ph.D. Associate Professor, Environmental Studies Center for Animals and Public Policy Tufts University School of Veterinary Medicine North Grafton, MA

David W. Scharp, M.D. Chief Scientific Officer Neocrin Company Irvine, CA

Steven Squinto, Ph.D. Vice-President of Research and Molecular Sciences Alexion Pharmaceuticals, Inc. New Haven, CT

Thomas Starzl, M.D. Professor of Surgery Director Pittsburgh Transplantation Institute University of Pittsburgh Pittsburgh, PA

M. Michael Swindle, D.V.M. Director, Division of Laboratory Animal Resources Professor and Chairman Department of Comparative Medicine Medical University of South Carolina Charleston, SC

James Walters, Ph.D. Professor of Christian Ethics Loma Linda University Claremont, CA

Mr. Calvin Wilkins Rumsey Island, MD

Mrs. Evelyn Wilkins Rumsey Island, MD

Stuart Youngner, M.D. Department of Medicine University Hospitals Cleveland, OH

Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 103
Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 104
Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 105
Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 106
Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 107
Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 108
Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 109
Suggested Citation:"Appendix A-Workshop Agenda." Institute of Medicine. 1996. Xenotransplantation: Science, Ethics, and Public Policy. Washington, DC: The National Academies Press. doi: 10.17226/5365.
×
Page 110
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Xenotransplantation: Science, Ethics, and Public Policy Get This Book
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Xenotransplantation involves the transplantation of cells, tissues, and whole organs from one species to another. Interest in animal-to-human xenotransplants has been spurred by the continuing shortage of donated human organs and by advances in knowledge concerning the biology of organ and tissue rejection. The scientific advances and promise, however, raise complex questions that must be addressed.

This book considers the scientific and medical feasibility of xenotransplantation and explores the ethical and public policy issues surrounding the possibility of renewed clinical trials. The volume focuses on the science base of xenotransplantation, public health risks of infectious disease transmission, and ethical and public policy issues, including the views of patients and their families.

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