Vaccines for the 21st Century: A Tool for Decisionmaking

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Table of Contents
Front Matter R1-R12
Executive Summary 1-10
Introduction 11-16
Progress in Vaccine Development 17-38
Considerations of Candidate Vaccines 39-52
Overview of Analytic Approach and Results 53-92
Review of the Analytical Model 93-108
Ethical Considerations and Caveats 109-122
Observations 123-132
References 133-142
Appendix 1: Borrelia burgdorferi 143-148
Appendix 2: Chlamydia 149-158
Appendix 3: Coccidioides Immitis 159-164
Appendix 4: Cytomegalovirus 165-172
Appendix 5: Enterotoxigenic E. coli 173-176
Appendix 6: Epstein-Barr Virus 177-180
Appendix 7: Helicobacter pylori 181-188
Appendix 8: Hepatitis C 189-194
Appendix 9: Herpes Simplex Virus 195-206
Appendix 10: Histoplasma capsulatum 207-212
Appendix 11: Human Paillomavirus 213-222
Appendix 12: Influenza A and B 223-232
Appendix 13: Insulin-Dependent Diabetes Mellitus 233-238
Appendix 14: Melanoma 239-244
Appendix 15: Multiple Sclerosis 245-250
Appendix 16: Mycobacterium tuberculosis 251-256
Appendix 17: Neisseria gonnorrhea 257-266
Appendix 18: Neisseria meningitidis 267-272
Appendix 19: Parainfluenza Virus 273-278
Appendix 20: Respiratory Syncytial Virus 279-284
Appendix 21: Rheumatoid Arthritis 285-290
Appendix 22: Rotavirus 291-294
Appendix 23: Shigella 295-298
Appendix 24: Streptococcus, Group A 299-304
Appendix 25: Streptococcus, Group B 305-312
Appendix 26: Streptococcus pneumoniae 313-322
Appendix 27: Information on accessing Electronic Spreadsheets 323-324
Appendix 28: Summary of Workshops 325-434
Appendix 29: Questions Posed to Outside Experts and List of Responders 435-442
Index 443-460

Table of Contents

Front Matter R1-R12

Executive Summary 1-10

Introduction 11-16

Progress in Vaccine Development 17-38

Considerations of Candidate Vaccines 39-52

Overview of Analytic Approach and Results 53-92

Review of the Analytical Model 93-108

Ethical Considerations and Caveats 109-122

Observations 123-132

References 133-142

Appendix 1: Borrelia burgdorferi 143-148

Appendix 2: Chlamydia 149-158

Appendix 3: Coccidioides Immitis 159-164

Appendix 4: Cytomegalovirus 165-172

Appendix 5: Enterotoxigenic E. coli 173-176

Appendix 6: Epstein-Barr Virus 177-180

Appendix 7: Helicobacter pylori 181-188

Appendix 8: Hepatitis C 189-194

Appendix 9: Herpes Simplex Virus 195-206

Appendix 10: Histoplasma capsulatum 207-212

Appendix 11: Human Paillomavirus 213-222

Appendix 12: Influenza A and B 223-232

Appendix 13: Insulin-Dependent Diabetes Mellitus 233-238

Appendix 14: Melanoma 239-244

Appendix 15: Multiple Sclerosis 245-250

Appendix 16: Mycobacterium tuberculosis 251-256

Appendix 17: Neisseria gonnorrhea 257-266

Appendix 18: Neisseria meningitidis 267-272

Appendix 19: Parainfluenza Virus 273-278

Appendix 20: Respiratory Syncytial Virus 279-284

Appendix 21: Rheumatoid Arthritis 285-290

Appendix 22: Rotavirus 291-294

Appendix 23: Shigella 295-298

Appendix 24: Streptococcus, Group A 299-304

Appendix 25: Streptococcus, Group B 305-312

Appendix 26: Streptococcus pneumoniae 313-322

Appendix 27: Information on accessing Electronic Spreadsheets 323-324

Appendix 28: Summary of Workshops 325-434

Appendix 29: Questions Posed to Outside Experts and List of Responders 435-442

Index 443-460