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Table A7–1 Incidence and Mortality Rates of H. pylori Infection

Age Groups

Population

% Distribution of Cases

Cases

INCIDENCE

 

<1

3,963,000

.0160

19,815

1–4

16,219,000

.1309

162,190

5–14

38,056,000

.3072

380,560

15–24

36,263,000

.2927

362,630

25–34

41,670,000

.1682

208,350

35–44

42,149,000

.0851

105,373

45–54

30,224,000

.0000

0

55–64

21,241,000

.0000

0

65–74

18,964,000

.0000

0

75–84

11,088,000

.0000

0

85+

3,598,000

.0000

0

Total

263,435,000

1,000

1,238,918

Age Groups

Population

% Distribution of Deaths

Cases

MORTALITY

 

<1

3,963,000

0.0004

6

1–4

16,219,000

0.0002

3

5–14

38,056,000

0.0001

2

15–24

36,263,000

0.0016

23

25–34

41,670,000

0.0085

431

35–44

42,149,000

0.0296

943

45–54

30,224,000

0.0647

1,781

55–64

21,241,000

0.1223

3,572

65–74

18,964,000

0.2453

4,510

75–84

11,088,000

0.3096

3,169

85+

3,598,000

0.2176

 

Total

263,435,000

1.0000

14,500

Disease Scenarios

For the purposes of the calculation in this report, the committee assumed that there are acute and chronic manifestations of H. pylori infection (see Table A7–2). Some of the chronic manifestations last for decades; others manifest for much shorter periods of time. It was assumed that 30% of people infected with H. pylori experience a week of acute gastritis. Half of those people go on to experience recurrent attacks of gastritis (approximately 2 days per month) for the lifetime of the person with no other complications. The health utility index (HUI) associated with gastritis was estimated to be .74. It was assumed that approximately 10% of infections are associated with approximately 30 years of recurrent gastritis, followed by peptic ulcer disease.



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