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Table A18–1 Incidence and Mortality Rates for Neisseria meningitidis B Epidemiology

Age Groups

Population

Incidence Rates (per 100,000)

% Distribution of Cases

<1

3,963,000

8.78

0.2900

1–4

16,219,000

1.48

0.2000

5–14

38,056,000

0.33

0.1057

15–24

36,263,000

0.33

0.1007

25–34

41,670,000

0.27

0.0927

35–44

42,149,000

0.20

0.0704

45–54

30,224,000

0.20

0.0505

55–64

21,241,000

0.20

0.0355

65–74

18,964,000

0.20

0.0317

75–84

11,088,000

0.20

0.0185

85+

3,598,000

0.20

0.0060

Total

263,435,000

0.46

1.0017

 

Total cases

1,200

Age Groups

Population

Mortality Rates (per 100,000)

% Distribution of Cases

<1

3,963,000

1.05

0.2900

1–4

16,219,000

0.18

0.2000

5–14

38,056,000

0.04

0.1057

15–24

36,263,000

0.04

0.1007

25–34

41,670,000

0.03

0.0927

35–44

42,149,000

0.02

0.0704

45–54

30,224,000

0.02

0.0505

55–64

21,241,000

0.02

0.0355

65–74

18,964,000

0.02

0.0317

75–84

11,088,000

0.02

0.0185

85+

3,598,000

0.02

0.0060

Total

263,435,000

0.05

1.0017

 

Total deaths

144

ence neurologic sequelae lasting a lifetime. These sequelae were estimated to be associated with an HUI of 0.6.

The committee estimated that 35% of new cases of NMB manifest as bacteremia and sepsis. Approximately half of these cases require ICU hospitalization, such as those with Waterhouse Friederichsen syndrome. The HUI associated with bacteremia range from 0.16 to 0.71. Approximately 5.25% of patients experience complications and just over 1% experiences sequelae, such as amputation, that last a lifetime.

Table A18–2 illustrates the estimated number of cases in each health state, the duration of time that state is experienced, and the HUI associated with each state.



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