. "Appendix 20: Respiratory Syncytial Virus." Vaccines for the 21st Century: A Tool for Decisionmaking. Washington, DC: The National Academies Press, 2000.
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Vaccines for the 21st Century: A Tool for Decisionmaking
Table 20–3 Health Care Costs Associated with RSV Infections
% with Care
Cost per Unit
Units per Case
Form of Treatment
AGE<5
Upper Respiratory
pharyngitis, otitis media
100%
$50
1.0
physician a
100%
$50
1.0
diagnostic a
100%
$50
1.0
medication b
Bronchiolitis/pneumonia
outpatient only
100%
$50
1.0
physician a
100%
$50
1.0
diagnostic a
100%
$50
1.0
medication b
Bronchiolitis/pneumonia
inpatient
100%
$4,000
1.0
hospitalization
100%
$50
2.0
physician a
100%
$50
1.0
diagnostic a
100%
$50
1.0
medication b
AGE 5+
Upper Respiratory
pharyngitis, otitis media
100%
$50
1.0
physician a
100%
$50
1.0
diagnostic a
100%
$50
1.0
medication b
Bronchiolitis/pneumonia
outpatient only
100%
$50
1.0
physician a
100%
$50
1.0
diagnostic a
100%
$50
1.0
medication b
Bronchiolitis/pneumonia
inpatient
100%
$4,000
1.0
hospitalization
100%
$50
2.0
physician a
100%
$50
1.0
diagnostic a
100%
$50
1.0
medication b
Vaccine Schedule, Efficacy, and Costs
For the purposes of the calculations in this report, it was estimated that this vaccine would cost $50 per dose and that administration costs would be $10 per dose. Default assumptions of a 3-dose series and 75% effectiveness were accepted. Table 4–1 summarizes vaccine program assumptions for all vaccines considered in this report.
RESULTS
If a vaccine program for RSV were implemented today and the vaccine were 100% efficacious and utilized by 100% of the target population, the annualized present value of the QALYs gained would be 33,000. Using committee assumptions of less-than-ideal efficacy and utilization and including time and monetary costs until a vaccine program is implemented, the annualized
