. "Appendix 26: Streptococcus pneumoniae." Vaccines for the 21st Century: A Tool for Decisionmaking. Washington, DC: The National Academies Press, 2000.
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Vaccines for the 21st Century: A Tool for Decisionmaking
Table A26–2 Disease Scenarios for Streptococcus pneumoniae Infection
No. of Cases
% of Cases
Committee HUI Values
Duration (years)
<5 YEARS OF AGE
Total Deaths (from acute infection)
1,450
Total Cases
6,381,306
BACTEREMIA/SEPSIS
6,216
0.10%
Bacteremia/Sepsis
1,243
0.02%
outpatient care only
0.93
0.0274 (10 days)
ICU
0.16
0.0055 (2 days)
inpatient after ICU
0.46
0.0137 (5 days)
Bacteremia/Sepsis—inpatient (no ICU)
3,730
0.06%
0.71
0.0110 (4 days)
Bacteremia/Sepsis—inpatient; complications
1,243
0.02%
0.59
0.0137 (5 days)
PNEUMONIA
62,161
0.97%
Pneumonia—outpatient care only
6,216
0.10%
0.82
0.0274 (10 days)
Pneumonia
55,944
0.88%
inpatient
0.71
0.0137 (5 days)
outpatient after inpatient
0.81
0.0137 (5 days)
Pneumonia with emphysema
932
0.01%
inpatient
0.64
0.0384 (14 days)
outpatient after inpatient
0.82
0.0384 (14 days)
OTHER RESPIRATORY
6,312,729
98.93%
Otitis Media
0.74
0.0110 (4 days)
Sinusitis, bronchitis
0.90
0.0274 (10 days)
MENINGITIS
200
0.0031%
Meningitis
160
0.003%
ICU
0.24
0.0055 (2 days)
inpatient after ICU
0.28
0.0274 (10 days)
Meningitis—inpatient (no ICU)
40
0.001%
0.39
0.0137 (5 days)
Meningitis—inpatient acute complications
30
0.0005%
0.27
0.0384 (14 days)
Meningitis—neurologic sequelae
60
0.001%
0.60
26.6824 (quality-adjusted life expectancy); 73.4869 (unadjusted life expectancy)
