Walter E.Stamm, M.D.

Division of Allergy and Infectious Diseases

University of Washington Medical Center

Seattle, WA

Stuart Starr, M.D.

Allergy, Immunology, and Infectious Diseases

Children’s Hospital

Philadelphia, PA

Dr. Allen Steere

Tufts University

Boston, MA

David A.Stevens, M.D.

Santa Clara Valley Medical Center

Division of Infectious Diseases

San Jose, CA

Dennis Stevens, M.D., Ph.D.

Veterans Affairs Medical Center

Boise, ID

Dr. Lode J.Swinnen

Section of Hematology/Oncology

Loyola University Medical Center

Maywood, IL

Martin A.Taubman, D.D.S., Ph.D.

Department of Immunology

Forsyth Dental Center

Boston, MA

Dr. Ram P.Tewari

Department of Microbiology and Immunology

Southern Illinois University

Springfield, IL

L.Joseph Wheat, M.D.

Wishard Memorial Hospital

Department of Medicine

Indianapolis, IN

Richard Whitley, M.D.

Pediatrics, Microbiology and Medicine

University of Alabama at Birmingham

Dr. Gary Wormser

Infectious Diseases

New York Medical College

Valhalla, NY

Peter F.Wright, M.D.

Pediatric Infectious Diseases

Vanderbilt University Medical Center

Nashville, TN

Dr. T.C.Wu

Johns Hopkins Hospital

Baltimore, MD

Michael Yancey, M.D.

Maternal-Fetal Medicine

Department of the Army

Headquarters, Tripler Army Medical Center

Tripler AMC, HI

Front Matter (R1-R12)

Executive Summary (1-10)

Introduction (11-16)

Progress in Vaccine Development (17-38)

Considerations of Candidate Vaccines (39-52)

Overview of Analytic Approach and Results (53-92)

Review of the Analytical Model (93-108)

Ethical Considerations and Caveats (109-122)

Observations (123-132)

References (133-142)

Appendix 1: Borrelia burgdorferi (143-148)

Appendix 2: Chlamydia (149-158)

Appendix 3: Coccidioides Immitis (159-164)

Appendix 4: Cytomegalovirus (165-172)

Appendix 5: Enterotoxigenic E. coli (173-176)

Appendix 6: Epstein-Barr Virus (177-180)

Appendix 7: Helicobacter pylori (181-188)

Appendix 8: Hepatitis C (189-194)

Appendix 9: Herpes Simplex Virus (195-206)

Appendix 10: Histoplasma capsulatum (207-212)

Appendix 11: Human Paillomavirus (213-222)

Appendix 12: Influenza A and B (223-232)

Appendix 13: Insulin-Dependent Diabetes Mellitus (233-238)

Appendix 14: Melanoma (239-244)

Appendix 15: Multiple Sclerosis (245-250)

Appendix 16: Mycobacterium tuberculosis (251-256)

Appendix 17: Neisseria gonnorrhea (257-266)

Appendix 18: Neisseria meningitidis (267-272)

Appendix 19: Parainfluenza Virus (273-278)

Appendix 20: Respiratory Syncytial Virus (279-284)

Appendix 21: Rheumatoid Arthritis (285-290)

Appendix 22: Rotavirus (291-294)

Appendix 23: Shigella (295-298)

Appendix 24: Streptococcus, Group A (299-304)

Appendix 25: Streptococcus, Group B (305-312)

Appendix 26: Streptococcus pneumoniae (313-322)

Appendix 27: Information on accessing Electronic Spreadsheets (323-324)

Appendix 28: Summary of Workshops (325-434)

Appendix 29: Questions Posed to Outside Experts and List of Responders (435-442)

Index (443-460)