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Vaccines for the 21st Century: A Tool for Decisionmaking
Court cases, see Liability issues;
Litigation
Cuba, 343
Cystic fibrosis, 33 , 42
Cytokines, 27 , 374 , 409–411 , 415 , 429–433
autoimmune disease, 36 , 38 , 389–392 , 404–405
chlamydia, 348–349
dengue virus, 344
gonorrhea, 371
Interleukin, 27 , 38 , 348–349 , 372 , 373 , 374 , 388 , 389 , 390–394 , 396 , 402–403 , 405–406 , 409 , 410 , 411–412 , 420 , 424 , 430 , 432
Cytomegalovirus (CMV), 6 , 19 , 20 , 22 , 54 , 87 , 89 , 90 , 165–171
D
Death rates, 377
as assessment criterion, 27
model, analytic approach, 61–62 , 66 , 68 , 78–79 , 80–83 , 86
model, detailed characterization, 95 , 97–98 , 100 , 103–104
chlamydia, 149
Coccidiodes immitis , 159 , 160 , 162
dengue virus, 343
gonorrhea, 257
Helicobacter pylori , 181 , 182
herpes simplex virus, 198
Histoplasma capsulatum , 207 , 208
influenza virus, 225–226
malaria, 43
melanoma, 239
meningitis, 267 , 268
mycobacterium tuberculosis, 252 , 253 , 351
parainfluenza virus, 273
polio, 24
papillomaviruses, 215
respiratory syncytial virus, 279 , 281 , 283
rheumatoid arthritis, 287
rotavirus, 291
streptococcus, group B, 305 , 307 , 309
Streptococcus pneumoniae 313 , 321
see also Life expectancy; Quality-adjusted life years
Dengue hemorrhagic fever, 342–347
Dental caries, 44–45
Delivery of vaccines, 130
adults, 47–50
antigens, various, 377–381
children, 45–47
DNA vaccines, 381–386
intranasal immunization
mycobacterium tuberculosis, 354
polio, 25–26
pregnant women, 50–51
see also Noninjection routes; Utilization of vaccines; Vaccine schedules
Demographic factors, 58
see also Age factors; Immigrants; Men; Race/ethnicity; Regional factors; Travelers; Urban areas; Women
Dengue hemorrhagic fever, 8
Department of Health and Human Services, 20–21
Centers for Disease Control and Prevention, 14 , 28 , 50 , 100
Food and Drug Administration, 14 , 125 , 126 , 362 , 367 , 373 , 374 ;
see also Licensure, vaccines
Health Care Financing Administration, 71 , 106
see also National Institutes of Health; specific institutes
Developing countries, 1 , 17 , 127–128 , 173 , 355 , 360
Diabetes mellitus, 6 , 35 , 37 , 54 , 67 , 87 , 90 , 233–238 , 386–389 , 391 , 392 , 393–395 , 403
Diptheria, 20 , 28 , 30 , 46 , 49
Disabilities, 63–66 , 68 , 78–79 , 86 , 89 , 97–98
cognitive impairments, 62 , 64–65
emotional impairments, 64–65
ethical factors, 111 , 112–113 , 114–115