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Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
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Appendixes

Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
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Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
×

Appendix A Acronyms and Abbreviations

AFRRI:

Armed Forces Radiobiology Research Institute

AGS:

Alternating gradient synchrotron

AP:

Apurinic or apyrimidinic

AT:

Ataxia telangiectasia

ATM:

AT mutated gene

BEIR:

Biological Effects of Ionizing Radiations, Committee on (National Research Council)

CNS:

Central nervous system

DNA:

Deoxyribonucleic acid

DNA-PK:

DNA-dependent protein kinase

DOD:

Department of Defense

DOE:

Department of Energy

DREF:

Dose rate effectiveness factor

EVA:

Extravehicular activity

GCR:

Galactic cosmic radiation

HPRT:

Hypoxanthine phosphoribosyl transferase

HZE:

High atomic number (Z) high energy

ICRP:

International Commission on Radiological Protection

LANL:

Los Alamos National Laboratory

LEO:

Low Earth orbit

LET:

Linear energy transfer

LQ:

Linear-quadratic

MIM:

Multiplicative interaction model

NASA:

National Aeronautics and Space Administration

NCRP:

National Council on Radiation Protection and Measurements

NER:

Nucleotide excision repair

NRC:

National Research Council

PCR:

Polymerase chain reaction

PK:

Protein kinase

Q:

Quality factor

RBE:

Relative biological effectiveness

RMS:

Root mean square

Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
×

SPE:

Solar particle event

TGBESR:

Task Group on the Biological Effects of Space Radiation

UNSCEAR:

United Nations Scientific Committee on the Effects of Atomic Radiation

USAF:

United States Air Force

WR:

Radiation weighing factor

XP:

Xeroderma pigmentosum

Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
×
Page 59
Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
×
Page 60
Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
×
Page 61
Suggested Citation:"Appendix A Acronyms and Abbreviations." National Research Council. 1996. Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies. Washington, DC: The National Academies Press. doi: 10.17226/5540.
×
Page 62
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NASA's long-range plans include possible human exploratory missions to the moon and Mars within the next quarter century. Such missions beyond low Earth orbit will expose crews to transient radiation from solar particle events as well as continuous high-energy galactic cosmic rays ranging from energetic protons with low mean linear energy transfer (LET) to nuclei with high atomic numbers, high energies, and high LET. Because the radiation levels in space are high and the missions long, adequate shielding is needed to minimize the deleterious health effects of exposure to radiation.

The knowledge base needed to design shielding involves two sets of factors, each with quantitative uncertainty—the radiation spectra and doses present behind different types of shielding, and the effects of the doses on relevant biological systems. It is only prudent to design shielding that will protect the crew of spacecraft exposed to predicted high, but uncertain, levels of radiation and biological effects. Because of the uncertainties regarding the degree and type of radiation protection needed, a requirement for shielding to protect against large deleterious, but uncertain, biological effects may be imposed, which in turn could result in an unacceptable cost to a mission. It therefore is of interest to reduce these uncertainties in biological effects and shielding requirements for reasons of mission feasibility, safety, and cost.

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