TABLE 4-9 Retrospective or Cross-Sectional Studies Concerning Lactation-Induced Bone Loss

Author

Year

N

Site

Alderman et al.

1986

355

562

Fracture Controls

Aloia et al.

1983

80

Radius

Cummings et al.

1995

173

137

Fracture Controls

Feldblum et al.

1992

352

Lumbar spine Radius

Hoffman et al.

1993

174

Fracture Controls

Hreshchyshyn et al.

1988

151

Lumbar spine

Kent et al.

1990

80

Radius

Koetting and Wardlaw

1988

28

Hip, Radius

Kreiger et al.

1982

98

884

Fracture Controls

Lissner et al.

1991

126

Lumbar spine

Melton et al.

1993b

304

Hip, Radius, Lumbar spine

Walker et al.

1972

102

Metacarpal

Wardlaw and Pike

1986

21

Radius

Wasnich et al.

1983

608

Radius

months (Sowers et al., 1995b). These findings support those from a cross-sectional study that found similar BMD among women with small or large families (Walker et al., 1972). Therefore, it does not appear, from the data available at this time, that closely spaced pregnancies lead to a lower bone mass in these women than in women with pregnancies less closely spaced.

Feeding More Than One Infant. A study in women breast-feeding twins found significantly higher serum PTH and 1,25(OH)2D concentrations compared to women nursing singletons. The authors suggest that these findings reflect an increased mineral need in the mothers (Greer et al., 1984). No studies have been reported in



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