models and their methodological limits is useful to clinicians in framing the questions about end-of-life decisionmaking for themselves, the other caregivers, patients, and their families. The more accurate the predictive models and the narrower the confidence limits, the more useful they will be. What cutoff point will be the appropriate cutoff point to decide that no more should be done will remain, I believe, an individual decision informed by, but not made exclusively by, these increasingly accurate predictive models.

I am indebted to my colleague, Dr. Jennifer Daley, for her contributions to the ideas in this essay.

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