NIH, NSF, and for the BCRP. The committee held discussions with past and present chairs and members of the Integration Panel regarding programmatic review processes and program policy decisions.

Staff members, under committee guidance, conducted an extensive literature search of various databases to attain a more "global" view of the topics currently being studied in breast cancer research and to delineate important areas in which programs are not in place or which would benefit from additional emphasis. Databases searched included Medline, Defense Technical Information Center (DTIC), Defense Research On-Line System (DROLS), the National Institutes of Health's Computer Retrieval of Information on Scientific Projects (CRISP), Federal Research in Progress (FedRIP), the GRANTS database for philanthropic organizations, and the Research and Development in the United States (RaDiUS) database developed by the Critical Technologies Institute at RAND.

Finally, the committee elicited written comments regarding the BCRP from FY 1993/1994 and FY 1995 grant recipients who responded to the committee's "Dear Colleague" mailing (see Appendix C and D). This effort was aimed at learning about investigators' experiences applying for and obtaining funds from the BCRP. Government confidentiality regulations precluded surveying all applicants (funded and unfunded). This range of activities provided the committee with a wealth of diverse information on which to base its deliberations. (The information collected is described in more detail in the appendixes.) This report presents the results of the committee's analyses and deliberations, its conclusions, and its recommendations. Chapter 1 provides the background for the study and the committee's charge, Chapter 2 focuses on breast cancer biology and medicine, Chapter 3 reviews non-BCRP support of breast cancer research, Chapter 4 focuses on the BCRP program, Chapter 5 discusses the funded portfolio of the FY 1993/1994 and FY 1995 BCRP award cycles, Chapter 6 provides the program critique, and Chapter 7 gives the committee's conclusions and recommendations.



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