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Emerging Technologies for Nutrition Research: Potential for Assessing Military Performance Capability (1997)
Institute of Medicine (IOM)

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. "7 Bioelectrical Impedance: A History, Research Issues, and Recent Consensus." Emerging Technologies for Nutrition Research: Potential for Assessing Military Performance Capability. Washington, DC: The National Academies Press, 1997.

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Emerging Technologies for Nutrition Research: Potential for Assessing Military Performance Capability

HISTORY

Impedance is the frequency-dependent opposition of a conductor to the flow of an alternating electric current. A measure of impedance (Z) is composed of the sum of two vectors, resistance (R) and reactance (Xc), measured at a particular frequency and is described mathematically by the equation Z2 = R2 + Xc2. Resistance is the opposition of a conductor to the alternating current, and as the electric current travels through the body, resistance is basically the same as in nonbiological conductors (Kay et al., 1954; Nyboer, 1959). Reactance is produced by the additional opposition to the current from the capacitant (storage) effects of cell membranes, tissue interfaces, and structural features (Baker, 1989; Barnett and Bagno, 1936; Schwan and Kay, 1956). The occurrence of these capacitant effects produced by the bilipid cell membrane reaches a peak and then declines as the current changes from low to high frequency. The phase angle (see Figure 7-1), which has been found to be important for describing relationships between bioelectrical impedance and the body and for measuring physiological variables (Baumgartner et al., 1988; Lukaski and Bolonchuk, 1987; Subramanyan et al., 1980), is expressed in degrees as the arctangent of the ratio of Xc/R and changes with changes in the frequency of the current.

Early studies of bioelectrical impedance focused on the meaning of impedance measures in relation to the water and electrolyte content of the body and to physiological variables such as thyroid function, basal metabolic rate, estrogenic activity, and blood flow in human and animal tissues (Barnett, 1937; Lukaski, 1987; Spence et al., 1979). These explorations developed into some of the

FIGURE 7-1 Impedance plot curve of resistance and reactance with frequency. Z, impedance; R, resistance; Xc, reactance; Hz, hertz; kHz, kilohertz. SOURCE: Chumlea and Baumgartner (1990), used with permission.

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Front Matter (R1-R18)
I Committee Summary and Recommendations (1-2)
1 Project Overview and Committee Summary (3-50)
2 Committee Responses to Questions, Conclusions and Recommendations (51-68)
II The Current Army Program and Its Future Needs (69-70)
3 Emerging Technologies in Nutrition Research for the Military: Overview of the Issues (71-78)
III Techniques of Body Composition Assessment (79-80)
4 Military Application of Body Composition Assessment Technologies (81-126)
5 Imaging Techniques of Body Composition: Advantages of Measurement and New Uses (127-150)
6 Dual-Energy X-Ray Absorptiometry: Research Issues, and Equipment (151-168)
7 Bioelectrical Impedance: A History, Research Issues, and Recent Consensus (169-192)
Part III Discussion (193-198)
IV Tracer Techniques for the Study of Metabolism (199-200)
8 Stable Isotope Tracers: Technological Tools That Have Emerged (201-214)
9 Measurement of Energy Substrate Metabolism Using Stable Isotopes (215-230)
10 Combined Stable Isotope-Positron Emission Tomography for In Vivo Assessment of Protein Metabolism (231-258)
11 Nuclear Magnetic Resonance Studies of Liver and Muscle Glycogen Metabolism in Humans (259-272)
Part IV Discussion (273-278)
V Ambulatory Techniques for Measurement of Energy Expenditure (279-280)
12 Doubly Labeled Water for Energy Expenditure (281-296)
13 Measurement of Oxygen Uptake with Portable Equipment (297-314)
14 Advances in Ambulatory Monitoring: Using Foot Contact Time to Estimate the Metabolic Cost of Locomotion (315-344)
15 Noninvasive Measurement of Plasma Metabolites Using Near-Infrared Spectroscopy (359-360)
Part V Discussion (361-362)
VI Molecular and Cellular Approaches to Nutrition (363-374)
16 The Role of Metals in Gene Expression (375-388)
17 Metabolic Regulation of Gene Expression (389-400)
18 Use of Isolated-Cell and Metabolic Techniques Applied to Vitamin Transport and Disposition (401-414)
19 Assessment of Cellular Dysfunction During Physiologic Stress (415-416)
VII Assessment of Immune Function (417-430)
20 The Validity of Blood and Urinary Cytokine Measurements for Detecting the Presence of Inflammation (431-450)
21 New Approaches to the Study of Abnormal Immune Function (451-500)
Part VI and VII Discussion (501-504)
VIII Functional and Behavioral Measures of Nutritional Status (505-506)
23 Involuntary Muscle Contraction to Assess Nutritional Status (507-518)
24 Application of Cognitive Performance Assessment Technology to Military Nutrition Research (519-532)
25 New Techniques for Assessment of Mental Performance in the Field (533-550)
26 The Iowa Driving Simulator: Using Simulation for Human Performance Measurement (551-568)
Part VIII Discussion (569-576)
Appendixes (577-578)
Appendix A: Workshop Agenda (579-584)
Appendix B: Biographical Sketches (585-604)
Appendix C: Abbreviations (605-608)
Appendix D: Emerging Technologies for Nutrition Research - A Selected Biography (609-680)
Index (681-711)