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Chapter 11 describes the use of nuclear magnetic resonance (NMR) spectroscopy for the investigation of both liver and muscle glycogen synthesis as well as the pathogenesis of Type II diabetes mellitus. This technique is based on the action of nuclei in the presence of a strong magnetic field, which in the end generates an image from released energy. For the purposes described here, NMR is noninvasive and safe but is relatively insensitive and expensive when the costs of the magnet and staff are considered. The use of NMR imaging for body composition analysis is described in Chapter 5 of this volume.



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