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Emerging Technologies for Nutrition Research: Potential for Assessing Military Performance Capability (1997)
Institute of Medicine (IOM)

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. "2 Committee Responses to Questions, Conclusions and Recommendations." Emerging Technologies for Nutrition Research: Potential for Assessing Military Performance Capability. Washington, DC: The National Academies Press, 1997.

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Emerging Technologies for Nutrition Research: Potential for Assessing Military Performance Capability

receiving significant support by federal and industrial funds should continue, and therefore, DoD investment is not recommended at this time.

  • Since military operations are frequently stressful and may be carried out in very hostile environments, it is important to understand the role that the body's immune function plays in helping the soldier cope and to consider ways in which immune responses may be controlled or enhanced to maximize the individual's ability to perform. Awareness of this research field and investment in selected research of potential significance to the military mission should be continued. The military must keep apprised of research findings on the influence of nutritional status on immune function.

  • Research on possible vaccine programs that may protect soldiers from infectious diseases frequently encountered in military operations should be supported, particularly when the potential infections are not usually a problem in the civilian sector. Oral vaccine development should be encouraged. Preliminary research at U.S. Army Medical Research Institute for Infectious Diseases to develop militarily important oral vaccines should be expanded. Research should be initiated or funded to develop transgenic plants that can produce antibodies against infections or toxins of unique military importance and to assess the influence of nutritional status on the response of military personnel to vaccinations.

  • The development of techniques and equipment that would permit evaluation of cognitive performance of individuals while actually performing their operational tasks should be supported, with the caveat that such techniques must be validated and as much information gathered as possible in controlled laboratory environments prior to field testing. When special modification is required for use in military equipment, support should be given to such development (for example, miniaturization).

The Committee on Military Nutrition Research is pleased to have participated with the Military Nutrition Division (currently the Military Nutrition and Biochemical Division), U.S. Army Research Institute of Environmental Medicine, and the U.S. Army Medical Research and Materiel Command in progress relating to the nutrition, performance, and health of U.S. military personnel. The CMNR hopes that this information will be valuable to the U.S. Department of Defense in developing programs that continue to improve the performance and lifelong health and well-being of service personnel.

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Front Matter (R1-R18)
I Committee Summary and Recommendations (1-2)
1 Project Overview and Committee Summary (3-50)
2 Committee Responses to Questions, Conclusions and Recommendations (51-68)
II The Current Army Program and Its Future Needs (69-70)
3 Emerging Technologies in Nutrition Research for the Military: Overview of the Issues (71-78)
III Techniques of Body Composition Assessment (79-80)
4 Military Application of Body Composition Assessment Technologies (81-126)
5 Imaging Techniques of Body Composition: Advantages of Measurement and New Uses (127-150)
6 Dual-Energy X-Ray Absorptiometry: Research Issues, and Equipment (151-168)
7 Bioelectrical Impedance: A History, Research Issues, and Recent Consensus (169-192)
Part III Discussion (193-198)
IV Tracer Techniques for the Study of Metabolism (199-200)
8 Stable Isotope Tracers: Technological Tools That Have Emerged (201-214)
9 Measurement of Energy Substrate Metabolism Using Stable Isotopes (215-230)
10 Combined Stable Isotope-Positron Emission Tomography for In Vivo Assessment of Protein Metabolism (231-258)
11 Nuclear Magnetic Resonance Studies of Liver and Muscle Glycogen Metabolism in Humans (259-272)
Part IV Discussion (273-278)
V Ambulatory Techniques for Measurement of Energy Expenditure (279-280)
12 Doubly Labeled Water for Energy Expenditure (281-296)
13 Measurement of Oxygen Uptake with Portable Equipment (297-314)
14 Advances in Ambulatory Monitoring: Using Foot Contact Time to Estimate the Metabolic Cost of Locomotion (315-344)
15 Noninvasive Measurement of Plasma Metabolites Using Near-Infrared Spectroscopy (359-360)
Part V Discussion (361-362)
VI Molecular and Cellular Approaches to Nutrition (363-374)
16 The Role of Metals in Gene Expression (375-388)
17 Metabolic Regulation of Gene Expression (389-400)
18 Use of Isolated-Cell and Metabolic Techniques Applied to Vitamin Transport and Disposition (401-414)
19 Assessment of Cellular Dysfunction During Physiologic Stress (415-416)
VII Assessment of Immune Function (417-430)
20 The Validity of Blood and Urinary Cytokine Measurements for Detecting the Presence of Inflammation (431-450)
21 New Approaches to the Study of Abnormal Immune Function (451-500)
Part VI and VII Discussion (501-504)
VIII Functional and Behavioral Measures of Nutritional Status (505-506)
23 Involuntary Muscle Contraction to Assess Nutritional Status (507-518)
24 Application of Cognitive Performance Assessment Technology to Military Nutrition Research (519-532)
25 New Techniques for Assessment of Mental Performance in the Field (533-550)
26 The Iowa Driving Simulator: Using Simulation for Human Performance Measurement (551-568)
Part VIII Discussion (569-576)
Appendixes (577-578)
Appendix A: Workshop Agenda (579-584)
Appendix B: Biographical Sketches (585-604)
Appendix C: Abbreviations (605-608)
Appendix D: Emerging Technologies for Nutrition Research - A Selected Biography (609-680)
Index (681-711)