Appendix

Workshop Agenda, Speakers, and Participants

Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations

Institute of Medicine

National Academy of Sciences

Committee on Pharmacokinetics and Drug Interactions in the Elderly

April 9, 1997

Xavier University of Louisiana

College of Pharmacy

New Orleans, LA

AGENDA

8:30–9:15 a.m.

Welcome

 

Marcellus Grace

Dean

College of Pharmacy

Xavier University of Louisiana

 

John Ruffin

Director

NIH Office of Research on Minority Health

 

J. Taylor Harden

Assistant to the Director for Special Populations

National Institute on Aging

 

Leslie Z. Benet, Committee Chair

University of California, San Francisco



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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary Appendix Workshop Agenda, Speakers, and Participants Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations Institute of Medicine National Academy of Sciences Committee on Pharmacokinetics and Drug Interactions in the Elderly April 9, 1997 Xavier University of Louisiana College of Pharmacy New Orleans, LA AGENDA 8:30–9:15 a.m. Welcome   Marcellus Grace Dean College of Pharmacy Xavier University of Louisiana   John Ruffin Director NIH Office of Research on Minority Health   J. Taylor Harden Assistant to the Director for Special Populations National Institute on Aging   Leslie Z. Benet, Committee Chair University of California, San Francisco

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary   Definition of the Elderly Population   Janice Schwartz Northwestern University Medical School MORNING SESSION State of the Science and Future Opportunities 9:15–10:00 a.m. Physiology of Aging   What are the age, gender, race, disease, and environment related factors influencing physiology as they impact pharmacotherapy?   Overview   Fran E. Kaiser St. Louis University   Hypertension in Elderly African Americans   Keith Ferdinand Xavier University of Louisiana 10:00–11:00 a.m. Intracellular Function   What are the age, gender, race, disease, and environment related factors influencing intracellular function as they impact pharmacotherapy?   Kinetics—Enzymes and Transport Proteins   Grant Wilkinson Vanderbilt University   Receptors   Physiologic   Darrell R. Abernethy Georgetown University Medical Center   Neurologic   Kurt Rasmussen Eli Lilly and Company, Inc. 11:00–11:30 a.m. DISCUSSION

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary   11:30 a.m.–12:15 p.m. Response and Outcomes   What are the age, gender, race, disease, and environment related factors influencing response and outcomes?   Response   Jeffrey Halter University of Michigan   Outcomes—Pharmacoepidemiology   Jane Cauley University of Pittsburgh   Economics of Pharmacotherapy   Andy Stergachis University of Washington 12:15–12:45 p.m. DISCUSSION 12:45–1:30 p.m. LUNCH AFTERNOON SESSION Resources and Opportunities What are the barriers and opportunities related to age, gender, race, disease, and the environment in pharmacotherapy research? 1:30–2:30 p.m. Recruitment of Study Participants   Defining the Study Population   Nanette Wenger Emory University   Greg Sachs University of Chicago   Issues in Recruiting and Retaining African   Americans in Clinical Trials   Techniques in Recruitment   Jackson Wright Case Western University   Compliance and Other Issues   Richard Corriveau Xavier University of Louisiana

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary 2:30–3:30 p.m. Chronic Medication Use   Pharmaceuticals   Bruce Pollock University of Pittsburgh   Nutraceuticals   Louis Lasagna Tufts University   Methodology   Wayne Ray Vanderbilt University 3:30–3:45 p.m. BREAK 3:45–4:00 p.m. Dissemination of Information to Prescribers, Pharmacists, Patients   Stephen Pauker New England Medical Center 4:00–4:20 p.m. Investigators/Funding   Jesse Roth Johns Hopkins University School of Medicine 4:20–5:10 p.m. DISCUSSION 5:10–5:30 p.m. Summary   Marcus Reidenberg Cornell University Medical Center 5:30 p.m. Adjourn

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary SPEAKERS Darrell R. Abernethy Francis Cabell Brown Professor of Medicine and Pharmacology Director Division of Clinical Pharmacology Georgetown University Medical Center Washington, DC Leslie Z. Benet Professor and Chairman Department of Biopharmaceutical Sciences University of California, San Francisco San Francisco, CA Jane Cauley Associate Professor Graduate School of Public Health University of Pittsburgh Pittsburgh, PA Richard Corriveau Director, Clinical Trials Unit College of Pharmacy Xavier University of Louisiana New Orleans, LA Keith Ferdinand Associate Professor, Clinical Pharmacology Medical Director, Heartbeats Life Center College of Pharmacy Xavier University of Louisiana New Orleans, LA Marcellus Grace Dean College of Pharmacy Xavier University of Louisiana New Orleans, LA Jeffrey Halter Director University of Michigan Geriatrics Center Ann Arbor, MI J. Taylor Harden Assistant Director for Special Populations National Institute on Aging Bethesda, MD Fran E. Kaiser Professor of Medicine Division of Geriatric Medicine St. Louis University Medical Center St. Louis, MO Louis Lasagna Dean for Scientific Affairs Tufts University School of Medicine Boston, MA Stephen G. Pauker Vice-Chairman for Clinical Affairs Department of Medicine New England Medical Center Boston, MA

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary Bruce Pollock Professor of Psychiatry and Pharmacology University of Pittsburgh School of Medicine Pittsburgh, PA Kurt Rasmussen Neuroscience Research Therapeutic Area Discovery Research and Clinical Investigation Eli Lilly & Company, Inc. Indianapolis, IN Wayne Ray Professor Department of Preventive Medicine and Public Health Vanderbilt University School of Medicine Nashville, TN Marcus M. Reidenberg Clinical Pharmacology and Therapeutics Cornell University Medical Center New York, NY Jesse Roth Raymond and Anna Lublin Professor of Medicine Director, Division of Geriatric Medicine Johns Hopkins University School of Medicine Baltimore, MD John Ruffin Director Office of Research on Minority Health National Institutes of Health Bethesda, MD Greg A. Sachs Assistant Professor of Medicine University of Chicago Medical Center Chicago, IL Janice B. Schwartz Professor of Medicine Chief of Clinical Pharmacology and Geriatric Medicine Northwestern University Medical School Chicago, IL Andy Stergachis Professor of Pharmacy and Epidemiology Chairman, Department of Pharmacy University of Washington School of Pharmacy Seattle, WA Nanette Wenger Professor of Medicine, Cardiology Emory University School of Medicine Atlanta, GA Grant R. Wilkinson Professor of Pharmacology Associate Director, Division of Clinical Pharmacology Vanderbilt University School of Medicine Nashville, TN Jackson T. Wright Director, Clinical Hypertension Program Department of Medicine Case Western Reserve University Cleveland, OH

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary PARTICIPANTS Edwin H. Adams School of Pharmacy Northeast Louisiana University West Monroe, LA Theodore R. Bates Professor of Pharmaceutics Texas Southern University Houston, TX Mark H. Beers Senior Director of Geriatrics Merck & Co., Inc. West Point, PA Levon Bostinian Assistant Professor College of Pharmacy Xavier University of Louisiana New Orleans, LA D. Craig Brater Chairman Department of Medicine Indiana University School of Medicine Indianapolis, IN Louise Cheung Assistant Professor of Pharmaceutics Texas Southern University Houston, TX Janice L. Feinberg Director American Society of Consultant Pharmacists (ASCP) Foundation Alexandria, VA David J. Greenblatt Professor and Chairman Department of Pharmacology and Experimental Therapeutics Tufts University Boston, MA Barbara E. Hayes College of Pharmacy and Health Sciences Texas Southern University Houston, TX Burde Kamath Associate Professor Biopharmaceutics and Pharmacokinetics College of Pharmacy Xavier University of Louisiana New Orleans, LA Patricia D. Kroboth Professor and Chair Department of Pharmaceutical Sciences University of Pittsburgh School of Pharmacy Pittsburgh, PA Catharyn T. Liverman Program Officer Institute of Medicine Washington, D.C. Henri R. Manasse, Jr. Executive Vice President American Society of Health System Pharmacists Bethesda, MD

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations: Workshop Summary C. David Matthews Assistant Professor Clinical Practice Northeast Louisiana University West Monroe, LA Joseph M. Moerschbaecher Professor and Head Department of Pharmacology Louisiana State University Medical Center New Orleans, LA Mark Monane Director Disease State Management-Geriatrics Merck Medco Managed Care Montvale, NJ Constance M. Pechura Director Division of Neuroscience and Behavioral Health Institute of Medicine Washington, D.C. Judith A. Salerno Chief Consultant Geriatrics and Extended Care Department of Veterans Affairs Washington, DC Daniel Sarpong ssistant Professor of Biostatistics College of Pharmacy Xavier University of Louisiana New Orleans, LA Marvin Scott Assistant Professor, Pharmacy Practice College of Pharmacy and Pharmaceutical Sciences Florida A&M University Tallahassee, FL Stanley Slater eputy Associate Director Geriatrics Program National Institute on Aging Washington, DC Robert Taylor Chairman Department of Pharmacology Howard University College of Medicine Washington, DC Vasant Telang Interim Dean College of Pharmacy Howard University Washington, DC Alice E. Till Vice President for Scientific Affairs Generic Pharmaceutical Industry Association Washington, DC