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OCR for page 192
Appendix
G
MECHANISMS USED IN OTHER COUNTRIES TO ENSURE
VACCINE SUPPLY
Country
Belgium
Canada
Denmark
Extent of Government Involvement
The Office Vaccinogene within the Ministere
de la Sante Publique et de la Famille is the
only government-sponsored establishment
producing vaccines. It produces only smallpox
vaccine, which, at present, is used to maintain
emergency stocks for Belgium.
While the government has no financial holding
in any vaccine manufacturer, it does maintain
adequate supplies of the following vaccines by
contracting with producers and importers: live
polio (oral); tetanus adsorbed; diphtheria and
tetanus adsorbed (DT); diphtheria, tetanus, and
pertussis adsorbed (DTP); measles, mumps, and
rubella (MMR), or combinations thereof; yellow
fever vaccine (for international travel); and
cholera and typhoid (for Army and international
travel).
The Ministry of Health also grants funds to
the Institut Pasteur du Brabant for production
of DTP, cholera, typhoid, and Bacillus Calmette-
Guerin (BCG) vaccines.
The government has minority shareholding in
Connaught Laboratories, Inc. through the
Canadian Development Corporation. This
shareholding will be returned to the private
sector in the future. The government is not
involved in company decision making.
The National Serum Institute, which provides
rcee vaccination against whooping cough, diph-
theria, polio, tetanus, and tuberculosis,
receives funds from the government treasury.
The Institute produces most of the vaccines and
imports a small amount. The Institute is cur-
rently the only vaccine manufacturer in Denmark.
_ . . . . . .
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193
Federal Republic The government has no financial involvement
of Germany in any vaccine production enterprise. In the
past, Land Vaccination Agencies produced
smallpox vaccine, but these were closed with the
discontinuance of smallpox vaccination.
France Rhone-Poulenc, a nationally-owned holding
company, has a 51 percent interest in Institut
Merieux. In Janury 1985, Institut Merieux
acquired a 51 percent interest in the Institut
Pasteur (production) and first rights to any
vaccine research from the Pasteur Foundation.
Japan
Netherlands
Sweden
Switzerland
Several independent manufacturers are subject
to fairly tight government controls.
All vaccines included in the national
immunization program (DTP-polio combination;
DT-polio combination; rubella; measles; and BCG
for high-risk groups) are produced at the
National Institute for Public Health and
Environmental Hygiene. In 1986, an MMR vaccine
will be included in the national program.
A state-owned institute manufactures or
procures vaccines.
There is no government involvement in the
Swiss Serum Institut.
United Kingdom The Centre for Applied Microbiology and
Research (of the Public Health Labor atorY
Service) is supported by government funds and
currently produces anthrax vaccine and botulism
toxoids for use in the United Kingdom. The
government is not involved financially in any
commercial production of vaccine. The Secretary
of State for Social Services can apply for and
hold product licenses for vaccines that
manufacturers choose not to hold. The Secretary
then arranges for production of such vaccines,
and may underwrite costs. The government also
purchases vaccine directly from manufacturers.
Representative terms from entire chapter:
smallpox vaccine