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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998)
Institute of Medicine (IOM)

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. "10 Pantothenic Acid." Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: The National Academies Press, 1998.

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DRI Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

is no basis for expecting an increased pantothenic acid requirement in the elderly, the AI is set at 5 mg/day—the same as for younger adults.

Pantothenic Acid AI Summary, Ages 51 Years and Older

AI for Men

51–70 years

5 mg/day of pantothenic acid

> 70 years

5 mg/day of pantothenic acid

AI for Women

51–70 years

5 mg/day of pantothenic acid

> 70 years

5 mg/day of pantothenic acid

Pregnancy

Evidence Considered in Setting the AI

There is little information on pantothenic acid requirements during pregnancy. In a longitudinal study of 26 pregnant women during their third trimester and at 2 weeks and 3 months postpartum, blood pantothenate concentrations were significantly lower than those of 17 nonpregnant control women, but there was no difference in daily urinary excretion during late pregnancy compared with control subjects (Song et al., 1985). Moreover, when data for unsupplemented women measured in the third trimester and again at 2 weeks postpartum were combined, average intake exceeded excretion across the range of intakes (mean dietary intake 5.3 ± 1.7 [SD] mg/day in pregnancy, 5.9 ± 2.0 [SD] mg/day in lactation, and 2 to 11 mg/day overall). In the absence of information showing that usual intakes in the United States and Canada are inadequate to support a healthy pregnancy outcome, and rounding up from this average intake, an AI of 6 mg/day of pantothenic acid is set for pregnant women.

Pantothenic Acid AI Summary, Pregnancy

AI for Pregnancy

14–18 years

6 mg/day of pantothenic acid

19–30 years

6 mg/day of pantothenic acid

31–50 years

6 mg/day of pantothenic acid

Page
367
Front Matter (R1-R24)
Summary (1-16)
1 Introduction to Dietary Reference Intakes (17-26)
2 The B Vitamins and Choline: Overview and Methods (27-40)
3 A Model for the Development of Tolerable Upper Intake Levels (41-57)
4 Thiamin (58-86)
5 Riboflavin (87-122)
6 Niacin (123-149)
7 Vitamin B6 (150-195)
8 Folate (196-305)
9 Vitamin B12 (306-356)
10 Pantothenic Acid (357-373)
11 Biotin (374-389)
12 Choline (390-422)
13 Uses of Dietary Reference Intakes (423-436)
14 A Research Agenda (437-442)
A Origin and Framework of the Development of Dietary Reference Intakes (443-447)
B Acknowledgments (448-450)
C Système International d'Unités (451-452)
D Search Strategies (453-455)
E Methodological Problems Associated with Laboratory Values and Food Composition Data for B Vitamins (456-459)
F Dietary Intake Data from the Boston Nutritional Status Survey, 1981–1984 (460-465)
G Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1995 (466-477)
H Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (478-501)
I Daily Intakes of B Vitamins by Canadian Men and Women, 1990, 1993 (502-506)
J Options for Dealing with Uncertainties in Developing Tolerable Upper Intake Levels (507-511)
K Blood Concentrations of Folate and Vitamin B12 from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (512-519)
L Methylenetetrahydrofolate Reductase (520-522)
M Evidence from Animal Studies on the Etiology of Neural Tube Defects (523-526)
N Estimation of the Period Covered by Vitamin B12 Stores (527-530)
O Biographical Sketches (531-536)
P Glossary and Abbreviations (537-540)
Index (541-567)