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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998)
Institute of Medicine (IOM)

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. "O Biographical Sketches." Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: The National Academies Press, 1998.

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DRI Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

vitamin B12 deficiency in the elderly in the United States. She is an associate editor of the Journal of Nutrition and was awarded the Kellogg International Nutrition Prize in 1997. Her other responsibilities on the Food and Nutrition Board include serving as chair of the Committee on International Nutrition and as a member of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes.

LYNN B.BAILEY, Ph.D., is a professor of nutrition in the University of Florida’s Food Science and Human Nutrition Department. Before joining the faculty in 1977, Dr. Bailey completed her Ph.D. and postdoctoral training at Purdue University in the area of human nutrient requirements. Her research has focused on the estimation of folate requirements and the evaluation of folate status in different life stages, including adolescence, young adulthood, pregnancy, and postmenopause. Collaborative studies involving folate labeled with stable isotopes have provided new information related to factors affecting folate bioavailability. Many scientific journal publications and book chapters have resulted from Dr. Bailey’s research, and she was editor of the book Folate in Health and Disease. She has served on numerous expert scientific panels, including the Food and Drug Administration’s Folate Subcommittee, which addressed the fortification of cereal grain products with folic acid in an effort to reduce the risk of neural tube defects. Dr. Bailey was the recipient of a national U.S. Department of Agriculture Award for Superior Service for her research accomplishments related to estimating folate requirements.

MERTON BERNFIELD, M.D., is an internationally recognized leader in developmental biology. Dr. Bernfield studies the molecular mechanisms underlying how organs take shape during embryonic development, which is important for understanding birth defects. He developed the most suitable mutant mouse model for human neural tube defects and has conducted research on prenatal care and birth outcome in blacks and whites. Dr. Bernfield serves as the Clement A.Smith Professor of Pediatrics and professor of cell biology at Harvard Medical School. Dr. Bernfield has received various honors, including Guggenheim and Macy fellowships, and distinguished lectureships, including the Swedish Zetterstrom Lecture, the Canadian Queen Elizabeth II Lecture and the Wellcome Visiting Professorship in the Basic Medical Sciences. He is a member of the Institute of Medicine, a fellow of the American Association for the Advancement of Sciences, and a member of the American Asso-

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532
Front Matter (R1-R24)
Summary (1-16)
1 Introduction to Dietary Reference Intakes (17-26)
2 The B Vitamins and Choline: Overview and Methods (27-40)
3 A Model for the Development of Tolerable Upper Intake Levels (41-57)
4 Thiamin (58-86)
5 Riboflavin (87-122)
6 Niacin (123-149)
7 Vitamin B6 (150-195)
8 Folate (196-305)
9 Vitamin B12 (306-356)
10 Pantothenic Acid (357-373)
11 Biotin (374-389)
12 Choline (390-422)
13 Uses of Dietary Reference Intakes (423-436)
14 A Research Agenda (437-442)
A Origin and Framework of the Development of Dietary Reference Intakes (443-447)
B Acknowledgments (448-450)
C Système International d'Unités (451-452)
D Search Strategies (453-455)
E Methodological Problems Associated with Laboratory Values and Food Composition Data for B Vitamins (456-459)
F Dietary Intake Data from the Boston Nutritional Status Survey, 1981–1984 (460-465)
G Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1995 (466-477)
H Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (478-501)
I Daily Intakes of B Vitamins by Canadian Men and Women, 1990, 1993 (502-506)
J Options for Dealing with Uncertainties in Developing Tolerable Upper Intake Levels (507-511)
K Blood Concentrations of Folate and Vitamin B12 from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (512-519)
L Methylenetetrahydrofolate Reductase (520-522)
M Evidence from Animal Studies on the Etiology of Neural Tube Defects (523-526)
N Estimation of the Period Covered by Vitamin B12 Stores (527-530)
O Biographical Sketches (531-536)
P Glossary and Abbreviations (537-540)
Index (541-567)