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Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (1998)
Institute of Medicine (IOM)

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. "Index." Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: The National Academies Press, 1998.

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DRI Dietary Reference Intakes: For Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline

B

Beriberi, 58, 59–60, 63, 65

Betaine, 392, 393, 398, 399, 413

Bioavailability of nutrients

biotin, 375–376, 378

choline, 400, 402, 413

correction factor, 328, 338

defined, 49, 537

factors affecting, 18, 62, 309, 338, 342, 375

folate, 8–9, 15, 16, 196, 208–210, 211, 221, 227, 235, 239, 256, 428

folic acid, 225, 235

form of intake and, 15, 16, 88, 208– 210, 211, 221, 235, 239, 343, 428

from infant formula, 30, 402

methodological issues, 210, 225

niacin, 123, 128–129, 133

nutrient-nutrient interactions and, 15

pantothenic acid, 361

riboflavin, 88, 95

and risk assessment, 49, 53

from supplements, 1, 9, 18, 49, 208, 210, 235, 256, 259, 331, 334

thiamin, 62

vitamin B6, 150, 160–161, 165, 177

vitamin B12, 309, 328, 338, 342, 343

BioRad Quantaphase Radioassay, 206

Biotin, 374–389

absorption, 376

adolescents, 381, 382–383

adults (19–50 years), 374, 380, 382–383, 385

adverse effects, 384–385

AIs, 6, 11, 21, 374, 380–383, 566–567

assay methods, 379

avidin and, 375–376, 379, 380

bioavailability, 375–376, 378

children, 381

deficiency, 375, 377–378

dose-response assessment for ULs, 385

elderly (>70 years). See Adults, >70 years

excretion, 377, 378

exposure assessment, 385

factors affecting requirement, 380

fetal, 377, 385

food composition data, 35, 36, 37, 459

food sources, 384

function, 11, 27, 374–375

gender differences, 382

hazard identification, 384–385

and 3-hydroxyisovalerate, 375, 378–379, 382, 383

indicators of adequacy, 11, 378–379

infants, 6, 56, 374, 377–378, 380–381

intakes, 38–39, 374, 384

laboratory values, 452, 457, 459

lactation and, 383

life-stage group and, 38–39, 380–383

metabolism, 377

methods used to set AIs, 380–383

neurological disorders, 377

and odd-chain fatty acid composition of plasma lipids, 379

older adults (51+ years), 382

plasma concentrations, 379

pregnancy and, 33, 380, 382–383, 385

research recommendations, 385–386, 440

risk characterization, 385

special considerations, 383

supplement use, 38–39, 384

transport, 376–377

ULs, 13, 56, 374, 384–385

unit conversions, 452

Biotin deficiency facies, 377–378

Biotinidase, 375, 380, 383

Blacks

glucose-6-dehydrogenase status, 108

homocysteine levels, 158

pernicious anemia, 317

riboflavin, 91, 106

vitamin B6, 174

Blood pressure. See Hypertension

Body Mass Index, 24, 25, 260

Body odor, 408, 411

Body weight. See also Reference body weight ratio method

and nutrient deficiency development, 129 n.1

reference weights, 24–26

thiamin pyrophosphate and, 75

Page
543
Front Matter (R1-R24)
Summary (1-16)
1 Introduction to Dietary Reference Intakes (17-26)
2 The B Vitamins and Choline: Overview and Methods (27-40)
3 A Model for the Development of Tolerable Upper Intake Levels (41-57)
4 Thiamin (58-86)
5 Riboflavin (87-122)
6 Niacin (123-149)
7 Vitamin B6 (150-195)
8 Folate (196-305)
9 Vitamin B12 (306-356)
10 Pantothenic Acid (357-373)
11 Biotin (374-389)
12 Choline (390-422)
13 Uses of Dietary Reference Intakes (423-436)
14 A Research Agenda (437-442)
A Origin and Framework of the Development of Dietary Reference Intakes (443-447)
B Acknowledgments (448-450)
C Système International d'Unités (451-452)
D Search Strategies (453-455)
E Methodological Problems Associated with Laboratory Values and Food Composition Data for B Vitamins (456-459)
F Dietary Intake Data from the Boston Nutritional Status Survey, 1981–1984 (460-465)
G Dietary Intake Data from the Continuing Survey of Food Intakes by Individuals (CSFII), 1994–1995 (466-477)
H Dietary Intake Data from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (478-501)
I Daily Intakes of B Vitamins by Canadian Men and Women, 1990, 1993 (502-506)
J Options for Dealing with Uncertainties in Developing Tolerable Upper Intake Levels (507-511)
K Blood Concentrations of Folate and Vitamin B12 from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994 (512-519)
L Methylenetetrahydrofolate Reductase (520-522)
M Evidence from Animal Studies on the Etiology of Neural Tube Defects (523-526)
N Estimation of the Period Covered by Vitamin B12 Stores (527-530)
O Biographical Sketches (531-536)
P Glossary and Abbreviations (537-540)
Index (541-567)