Assessment of Exposure-Response Functions for Rocket-Emission Toxicants

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Assessment of Exposure-Response Functions for Rocket-Emission Toxicants (1998)
Commission on Life Sciences (CLS)

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. "Effect Severity." Assessment of Exposure-Response Functions for Rocket-Emission Toxicants. Washington, DC: The National Academies Press, 1998.

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Assessment of Exposure-Response Functions for Rocket-Emission Toxicants

TABLE 4-1 Classification of Potential Signs, Symptoms, and Effects of Human Exposure to Rocket-Emission Toxicants

Outcome	Mild	Moderate	Severe
Perception of odor or taste	√
Headache	Nonrecurring	Increased frequency	Incapacitating
Eye irritation	Discomfort	Burning sensation
Tearing (by itself)	√
Corneal Opacity			√
Nasal irritation	Discomfort	Burning sensation
Sneezing	√
Nasal catarrh	√
Rhinorrhea	√
Miosis	√
Cough	Infrequent	Frequent	Incapacitating
Burning throat			√
Spasm of larynx			√
Tightness in chest	√
Increased airway resistance	√	√	√
Increased airway responsiveness	√	√	√
Increased sputum production	√	√
Wheezing, in absence of cold		√	√
Bronchospasm			√
Sloughing of airway lining		√	√
Rhonchi			√
Bronchiolitis	√	√	√
Focal pneumonia	√	√
Diffuse pneumonia		√	√
Chemical pneumonitis		√	√
Chest pain			√
Shortness of breath		√
Difficulty breathing		√	√
Increase in methemoglobin	√	√	√
Increase in blood pressure	√	√	√
Increase in blood glutathione levels	√
Decrease in CO diffusion capacity	√	√	√
Decrease in lung compliance	√	√	√
Decrease in earlobe blood PO₂	√	√	√
Decrease in alveolar O₂ partial pressure	√	√	√
Pulmonary edema		√	√
Asthma attack	√	√	√
Disorientation		√	√
Exacerbation of chronic cardiopulmonary disease			√