• Identify critical gaps in knowledge that should be filled by future research.

To accomplish the charge suggested here, the membership of the committee responsible for the proposed BEIR VII phase-2 study will require expertise in epidemiology, biostatistics, radiation physics and dosimetry, molecular biology, risk assessment and communication, cancer modeling, animal and cellular radiation biology, somatic cell genetics, cell-cycle regulation and apoptosis, and the causation and repair of DNA damage induced by ionizing radiation. The committee recommends that the experts chosen have adequate resources and access to data for the computing, statistical analyses, and modeling required to complete the study. A major goal of the BEIR VII phase-2 study will be to better quantify and characterize the uncertainties associated with risk estimates and to produce the most realistic estimates of uncertainties.



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