Information on Committee Members

RICHARD B. SETLOW (Chairman) is a Senior Biophysicist and the Associate Director for Life Sciences at the Brookhaven National Laboratory. He received his Ph.D. in Physics from Yale. Shortly thereafter he began Biophysics research on the effects of ionizing radiation and ultraviolet radiation on proteins and DNA. This work led to investigations of radiation effects on viruses and microbial cells. After teaching Physics and Biophysics for a number of years he moved to the Biology Division of the Oak Ridge National Laboratory where he and his colleagues discovered Nucleotide Excision Repair—the first DNA repair mechanism that worked in the dark. His subsequent experiments dealt with the effects of radiation on human cells and the variances among humans, as measured on lymphocytes, of the responses and repair of chemical, ultraviolet and ionizing radiation damage to DNA. His present research deals with the spectral regions that induce malignant melanomas in fish-a surrogate for humans. Dr. Setlow was President of the Biophysical Society in 1969-1970. He is a member of numerous scientific societies including the National Academy of Sciences and the American Society for Cancer Research. For a number of years he was a member and the chairman of the Scientific Advisory Board of the National Center for Toxicological Research and is now a member of the Science Board of the FDA. He was the chairman of two committees that recently issued National Academy Press Reports — Mortality of Veterans in the Crossroads Nuclear Test (1996) and Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies (1996). Dr. Setlow is the recipient of the Finsen Medal from the International Association for Photobiology and the Enrico Fermi Award from the Department of Energy.

KENNETH H.HADWICK is the Head of Sector with the Radiation Protection Research Unit, Directorate General for Science, Research and Development, European Commission. He graduated with a B.Sc. in Physics from Liverpool University, UK and earned a M.Sc. in Radiation Biophysics from the University of London, UK. He was awarded a Ph.D. by the University of Utrecht in the Netherlands. He worked in research on cellular radiation biology for over twenty years and is co-author of over seventy articles and a book on theoretical radiation biology. Dr. Chadwick is currently Head of Sector responsible for the management of Radiation Biology and Health Effects research contracts in the Nuclear Fission Safety Programme of the European Commission in Brussels. Dr. Chadwick is a Fellow of the Institute of Physics, UK; a Fellow of the Society for Radiological Protection, UK; a Member of the Radiation Research Society, USA; and a Member of the European Physical Society.

PHILIP C. HANAWALT is the Howard and Jessie Watkins University Professor in the Department of Biological Sciences at Stanford, with a joint appointment in the Dermatology Department, Stanford Medical School. He earned his Ph.D. in Biophysics at Yale University and has received an honorary Sc.D. from his alma mater, Oberlin College. He has served as Director of the Biophysics Graduate Program and as Chair of the Department of Biological Sciences at Stanford. He has trained 25 Ph.D. students and over 60 postdoctoral research fellows from over 20 countries. He has served as President



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Health Effects of Exposure to Low Levels of Ionizing Radiations: Time for Reassessment? Information on Committee Members RICHARD B. SETLOW (Chairman) is a Senior Biophysicist and the Associate Director for Life Sciences at the Brookhaven National Laboratory. He received his Ph.D. in Physics from Yale. Shortly thereafter he began Biophysics research on the effects of ionizing radiation and ultraviolet radiation on proteins and DNA. This work led to investigations of radiation effects on viruses and microbial cells. After teaching Physics and Biophysics for a number of years he moved to the Biology Division of the Oak Ridge National Laboratory where he and his colleagues discovered Nucleotide Excision Repair—the first DNA repair mechanism that worked in the dark. His subsequent experiments dealt with the effects of radiation on human cells and the variances among humans, as measured on lymphocytes, of the responses and repair of chemical, ultraviolet and ionizing radiation damage to DNA. His present research deals with the spectral regions that induce malignant melanomas in fish-a surrogate for humans. Dr. Setlow was President of the Biophysical Society in 1969-1970. He is a member of numerous scientific societies including the National Academy of Sciences and the American Society for Cancer Research. For a number of years he was a member and the chairman of the Scientific Advisory Board of the National Center for Toxicological Research and is now a member of the Science Board of the FDA. He was the chairman of two committees that recently issued National Academy Press Reports — Mortality of Veterans in the Crossroads Nuclear Test (1996) and Radiation Hazards to Crews of Interplanetary Missions: Biological Issues and Research Strategies (1996). Dr. Setlow is the recipient of the Finsen Medal from the International Association for Photobiology and the Enrico Fermi Award from the Department of Energy. KENNETH H.HADWICK is the Head of Sector with the Radiation Protection Research Unit, Directorate General for Science, Research and Development, European Commission. He graduated with a B.Sc. in Physics from Liverpool University, UK and earned a M.Sc. in Radiation Biophysics from the University of London, UK. He was awarded a Ph.D. by the University of Utrecht in the Netherlands. He worked in research on cellular radiation biology for over twenty years and is co-author of over seventy articles and a book on theoretical radiation biology. Dr. Chadwick is currently Head of Sector responsible for the management of Radiation Biology and Health Effects research contracts in the Nuclear Fission Safety Programme of the European Commission in Brussels. Dr. Chadwick is a Fellow of the Institute of Physics, UK; a Fellow of the Society for Radiological Protection, UK; a Member of the Radiation Research Society, USA; and a Member of the European Physical Society. PHILIP C. HANAWALT is the Howard and Jessie Watkins University Professor in the Department of Biological Sciences at Stanford, with a joint appointment in the Dermatology Department, Stanford Medical School. He earned his Ph.D. in Biophysics at Yale University and has received an honorary Sc.D. from his alma mater, Oberlin College. He has served as Director of the Biophysics Graduate Program and as Chair of the Department of Biological Sciences at Stanford. He has trained 25 Ph.D. students and over 60 postdoctoral research fellows from over 20 countries. He has served as President

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Health Effects of Exposure to Low Levels of Ionizing Radiations: Time for Reassessment? of the Environmental Mutagen Society and on the Board of Directors of the American Association for Cancer Research. He has served as a managing editor for Mutation Research and is currently a member of the Board of Reviewing Editors for Science. He serves on numerous advisory boards including that of the Fogarty International Center (NIH), the Office of Environmental Health Hazard Assessment (California EPA), and the toxicology advisory committee for the Burroughs-Welcome Fund. Dr. Hanawalt's specialty is photobiology and DNA repair, having co-discovered excision-repair and more recently the pathway of transcription-coupled repair. He has received an outstanding investigator award from the National Cancer Institute and in 1989 was elected to the National Academy of Sciences. He is presently a member of the Board on Radiation Effects Research in the National Research Council. GEOFFREY R. HOWE is Professor of Public Health and Head, Division of Epidemiology at Columbia University School of Public Health. Dr. Howe earned his Ph.D. degree from the University of Leicester. He was formerly professor at the University of Toronto and Director of the National Cancer Institute of Canada Epidemiology Unit. He is a member of the National Commission for Radiological Protection and measurements and served as consultant or member on the last three BEIR Committees. He is a member of the editorial boards of Cancer Causes and Control and Cancer Epidemiology, Biomarkers and Prevention . Dr. Howe's radiation studies include those of tuberculosis patients exposed to low-LET radiation, miners exposed to radon, nuclear workers, and the National Cancer Institute sponsored studies of the consequences of the Chernobyl accident. He has acted as an adviser to the World Health Organization with respect to Chernobyl studies and serves on the Department of Energy's scientific review group for the latter's joint American/Russian radiation studies. ALBRECHT M. KELLERER is the Director of the Radiobiological Institute of the University of Munich and of the Institute of Radiation Biology of the GSF, National Research Center for Environment and Health. He was formerly professor of radiation biophysics at Columbia University in New York, and subsequently professor and chief of the Institute for Medical Radiation Research at the University of Wurzburg. Dr. Kellerer's research specialties include microdosimetry, radiation risk assessment, and radiobiology. Dr. Kellerer is a member of the German National Commission for Radiation Protection, chairman of its committee for risk assessment and a member of committees of the ICRU and the International Commission on Radiological Protection. Dr. Kellerer is also the managing editor of the Journal of Radiation and Environmental Physics. CHARLES E. LAND is a statistician at the National Cancer Institute's Radiation Epidemiology Branch. His research interests include radiation carcinogenesis and statistical methods. In addition to the NCI, Dr. Land has worked for organizations such as Los Alamos Scientific Laboratory, Bell Telephone Laboratories, and the Atomic Bomb Casualty Commission. Dr. Land has received scientific recognition for his work and is a member of numerous professional societies such as the Radiation Research Society, the American College of Epidemiology, and the American Society for the Advancement of Science.