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Health Effects of Exposure to Low Levels of Ionizing Radiations: Time for Reassessment? NANCY L. OLEINICK is Professor and Director of the Division of Radiation Biology in the Department of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, Ohio, and Director of the Radiation Biology Program of the CWRU/Ireland Cancer Center. She earned her Ph.D. in Biochemistry from the University of Pittsburgh. Dr. Oleinick's research specialties are in radiobiology and photobiology. One long-term research interest concerns the role of chromatin structure and the nuclear matrix in determining the microheterogeneity of radiation damage to DNA, DNA repair, and the cellular responses to ionizing radiation. Recent research has also focused on the cellular and molecular effects of photosensitization related to photodynamic therapy. Dr. Oleinick has served on the Editorial Boards of Radiation Research, International Journal of Radiation Biology, and Photochemistry and Photobiology, on the US National Institutes of Health Radiation Study Section, and on the Board of Scientific Counselors, Division of Cancer Etiology, National Cancer Institute. She is currently President-Elect of the American Society for Photobiology. Dr. Oleinick has been a member of numerous other review panels considering radiation effects, including the Presidential Advisory Committee on Human Radiation Experiments and the Veterans' Advisory Committee on Environmental Hazards. ROBERT L. ULLRICH is the Vincent P. Collins Distinguished Professor in Radiation Oncology Research and Director of the Biology Division in the Department of Radiation Oncology at the University of Texas Medical Branch. Dr. Ullrich earned his Ph.D. from the University of Rochester School of Medicine and Dentistry. He was formerly head of the Radiation Carcinogenesis Unit at the Oak Ridge National Laboratory. He is a member of the Board of Directors of the National Council on Radiation Protection and Measurements and a Member of the Council of the Radiation Research Society. He received the Research Award of the Radiation Research Society in 1987. Dr. Ullrich has served on the National Research Council Panel on Space Radiation Effects, a number of National Institutes of Health advisory committees, and on the International Commission on Radiological Protection Task Group on estimates of radiation-induced cancer at low doses. List of Acronyms AP apurinic-apyrimidinic AT ataxia telangiectasia ATM the protein mutated in ataxia telangiectasia BEIR Biological Effects of Ionizing Radiations (refers to a series of studies conducted by committees of the National Research Council). BrdU bromodeoxyuridine BRER Board on Radiation Effects Research (of the National Research Council) DDKEFdose and dose-rate effectiveness factor
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