showering, 57, 85-92, 255

transfer coefficients, 13, 15, 25, 30-31, 50-58, 126, 133-134, 143, 182, 229, 261

uncertainties, 18, 132-133

see also Aerosol characteristics

AIRDOSE model, 162

Alternative maximum contaminant level, 2-5 (passim), 10, 20-21, 31, 180-188 (passim), 196, 223

Angiogenesis, 119, 223

Ambient radon, 10, 12-13, 19, 37-49, 182

uncertainties, 132-133

see also Airborne radon

American Water Works Association, 56, 166

Apoptosis, 105, 106, 113, 115, 116-118, 121, 223

Apurinic site, 114

Atom bomb survivors, 28, 77-78, 80-81, 95, 131, 137

Attributable risk, 16, 100, 135, 223, 263

B

Background exposure, 1, 8, 23, 37-49, 105

Backwashing, 165, 167, 169, 172, 175-176, 178, 223, 252

Basements, houses with, 1, 33, 141, 142, 145, 146, 147, 148-149, 152, 155, 156, 157

Bayesian models, 33

BEIR IV report, 17, 93, 95-96, 99, 103

BEIR VI report, 13, 15, 16, 17, 83, 93, 94, 95, 99-100, 103, 122, 131, 134-135

Best-available technology, 20

aeration, 161, 179

alternative maximum contaminant level, 181

blending, 177

granular activated carbon, 168, 174, 179, 263

national ambient average concentration, 13, 132-133

reverse osmosis, 177

Biologic processes, general, 13-14, 63-76, 131

see also Embryos;

Carcinogenesis and carcinogens;

Cells and cellular processes;

Molecular processes

Blending (water treatment), 177, 179

Blood and blood vessels, 27, 63, 75, 81, 84, 107, 119-120, 136, 241

hematopoietic processes, 120, 225

PBPK models, 14, 31, 66-72, 76, 227, 233-240

Bone and skeletal system, 63, 78, 79, 80, 85, 239, 251

Breasts, 75, 76, 78, 79, 80, 100, 113, 118, 119

Breathing rate, 27, 83, 84, 103, 128, 261

Bronchi, dosimetry, 15, 82, 83, 91-92, 107-108

Building materials, see Construction materials and practices

C

CARBDOSE, 171, 259

Carcinogens and carcinogenesis, 105-123

defined, 224

disinfection byproducts, 165-166, 254-256

see also Cells and cellular processes;

Genetics;

Lungs and lung cancer;

Molecular processes;

Stomach;

other specific cancers

Caspases, 116-117, 224

Cells and cellular processes, 13-14, 28, 73, 84, 97, 105-123, 131, 224

apoptosis, 105, 106, 113, 115, 116-118, 121, 223

basal cells, 119

crypts, 107, 224, 241, 245, 248

cytokines, 108, 117, 224

doses and dosimetry, 105, 107-108, 109-110, 115-116, 120-123

endogenous, 109, 116, 120

hematopoietic, 120, 225

in vitro studies, 64, 110, 121

in vivo studies, 121

mitochondria, 109, 226

preneoplastic, 120, 228

proliferation, 107, 118, 119-120, 121, 122, 131,228, 241

regulatory, 105, 113, 114, 115-116, 118, 119, 120, 121, 131

repair, 28, 93, 106, 107, 110-114, 115-116, 118, 199

secretory, 71-72, 105, 107, 119, 135, 241

signal transduction, 108, 111, 112, 113, 116, 117-118, 119, 229



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