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showering, 57 , 85-92 , 255
transfer coefficients, 13 , 15 , 25 , 30-31 , 50-58 , 126 , 133-134 , 143 , 182 , 229 , 261
uncertainties, 18 , 132-133
see also Aerosol characteristics
AIRDOSE model, 162
Alternative maximum contaminant level, 2-5 (passim), 10 , 20-21 , 31 , 180-188 (passim), 196 , 223
Angiogenesis, 119 , 223
Ambient radon, 10 , 12-13 , 19 , 37-49 , 182
uncertainties, 132-133
see also Airborne radon
American Water Works Association, 56 , 166
Apoptosis, 105 , 106 , 113 , 115 , 116-118 , 121 , 223
Apurinic site, 114
Atom bomb survivors, 28 , 77-78 , 80-81 , 95 , 131 , 137
Attributable risk, 16 , 100 , 135 , 223 , 263
B
Background exposure, 1 , 8 , 23 , 37-49 , 105
Backwashing, 165 , 167 , 169 , 172 , 175-176 , 178 , 223 , 252
Basements, houses with, 1 , 33 , 141 , 142 , 145 , 146 , 147 , 148-149 , 152 , 155 , 156 , 157
Bayesian models, 33
BEIR IV report, 17 , 93 , 95-96 , 99 , 103
BEIR VI report, 13 , 15 , 16 , 17 , 83 , 93 , 94 , 95 , 99-100 , 103 , 122 , 131 , 134-135
Best-available technology, 20
aeration, 161 , 179
alternative maximum contaminant level, 181
blending, 177
granular activated carbon, 168 , 174 , 179 , 263
national ambient average concentration, 13 , 132-133
reverse osmosis, 177
Biologic processes, general, 13-14 , 63-76 , 131
see also Embryos;
Carcinogenesis and carcinogens;
Cells and cellular processes;
Molecular processes
Blending (water treatment), 177 , 179
Blood and blood vessels, 27 , 63 , 75 , 81 , 84 , 107 , 119-120 , 136 , 241
hematopoietic processes, 120 , 225
PBPK models, 14 , 31 , 66-72 , 76 , 227 , 233-240
Bone and skeletal system, 63 , 78 , 79 , 80 , 85 , 239 , 251
Breasts, 75 , 76 , 78 , 79 , 80 , 100 , 113 , 118 , 119
Breathing rate, 27 , 83 , 84 , 103 , 128 , 261
Bronchi, dosimetry, 15 , 82 , 83 , 91-92 , 107-108
Building materials, see Construction materials and practices
C
CARBDOSE, 171 , 259
Carcinogens and carcinogenesis, 105-123
defined, 224
disinfection byproducts, 165-166 , 254-256
see also Cells and cellular processes;
Genetics;
Lungs and lung cancer;
Molecular processes;
Stomach;
other specific cancers
Caspases, 116-117 , 224
Cells and cellular processes, 13-14 , 28 , 73 , 84 , 97 , 105-123 , 131 , 224
apoptosis, 105 , 106 , 113 , 115 , 116-118 , 121 , 223
basal cells, 119
crypts, 107 , 224 , 241 , 245 , 248
cytokines, 108 , 117 , 224
doses and dosimetry, 105 , 107-108 , 109-110 , 115-116 , 120-123
endogenous, 109 , 116 , 120
hematopoietic, 120 , 225
in vitro studies, 64 , 110 , 121
in vivo studies, 121
mitochondria, 109 , 226
preneoplastic, 120 , 228
proliferation, 107 , 118 , 119-120 , 121 , 122 , 131,228 , 241
regulatory, 105 , 113 , 114 , 115-116 , 118 , 119 , 120 , 121 , 131
repair, 28 , 93 , 106 , 107 , 110-114 , 115-116 , 118 , 199
secretory, 71-72 , 105 , 107 , 119 , 135 , 241
signal transduction, 108 , 111 , 112 , 113 , 116 , 117-118 , 119 , 229