there would be only a 29% decline in the number of HIV-infected babies (i.e., from 1,172 to 830). Here it is assumed that 92.5% of HIV-infected pregnant women obtained early prenatal care, 87.5% of women were offered HIV testing, 90% of women accepted testing, 95% of HIV-positive women were offered ZDV, and 95% of women accepted and complied with ZDV therapy. To achieve a further 50% decline in the number of HIV-infected babies (i.e., from 1,172 to 580 infected babies) and be within reach of the currently achievable state (i.e., 350 infected babies), the gap between observed and achievable rates would have to close by 78%, and rates for factors related to transmission would have to be very high (e.g., 96.7% of women with prenatal care) (column 9).

References

Birkhead GS. New York State AIDS Institute. Personal communication. 1998.


Gorsky RD, Farnham PG, Straus WL, Caldwell B, Holtgrave DR, Simonds RJ, Rogers MF, Guinan ME. Preventing perinatal transmission of HIV: Costs and effectiveness of a recommended intervention. Public Health Rep 111(4):335–341, 1996.


Mauskopf JA, Paul JE, Wichman DS, White AD, Tilson HH. Economic impact of treatment of HIV-positive pregnant women and their newborns with zidovudine. Implications for HIV screening. JAMA 276(2):132–138, 1996.

Myers ER, Thompson JW, Simpson K. Cost–effectiveness of mandatory compared with voluntary screening for human immunodeficiency virus in pregnancy. Obstet Gynecol 91(2):164–181, 1998.


Pins MR, Teruya J, Stowell CP. Human immunodeficiency virus testing and case detection: pragmatic and technical issues. In: Cotton D and Watts DH, eds. The Medical Management of AIDS in Women. Wiley-Liss: New York City, 1996.



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