might be expected, given the research status of most of the entries, there is no evidence or only partial evidence of efficacy in 53% of the treatment products. There is evidence of efficacy in animals in 21% of the entries, but only 3 (4%) entries with proven efficacy in humans.
The chemical agents considered for this inventory are: cyanide, nerve agents, phosgene, and vesicants. Out of the 40 treatment products in the inventory, 43% are for nerve agents, 30% for cyanide, 15% for vesicants, and 12% for phosgene. There is currently only one IND and it is for a cyanide treatment. As in biological treatments, most (53%) treatment products for chemical agents are in the preclinical stage of development; however, 35% of the chemical agent treatments are commercially available in the United States. There is animal evidence of efficacy in 68% of the entries, and 8 (20%) proven treatments in humans. The remaining products have no evidence or only partial evidence of efficacy.
This is a unique section of the inventory because the committee was unable to identify any "products" specifically connected with chemical or biological terrorism. The inventory thus focuses on information and resources regarding the psychological effects and treatment of trauma and disasters in general. There are 16 entries ranging from Web sites, to current studies, to publications. One entry focuses solely on rescue and health care workers; 4 solely on trauma victims themselves; and 2 focus on community-wide effects. The remaining seven include more than one of the above in their scopeusually victims and workers. Unfortunately, there is a dearth of information and resources about specific populations of victims such as the elderly, children, the disabled, and other special groups outside of the average adult male and female.
The 20 items in this database fall in two main categories: (1) information about agent transport, and (2) information about incident management. There are 10 models in each category. Most (13) are in beta testing, 4 are available for use at this time or are being used for purposes other than assisting authorities plan for responding to chemical or biological terrorism, and three are in the planning stage. The Department of Defense is funding 15 products, DoE 3, EPA 1, and 1 is funded by a commercial organization.