patients. Of the more than 3,300 men participating in the study, approximately 500 African-American and 430 Hispanic men participated in the initial survey. Finally, feasibility studies are being conducted to examine patterns of care from several data sources, including the Indian Health Service, to provide more information on American Indian cancer patients, particularly those suffering from colon, lung, breast, prostate, and cervical cancers.

Epidemiologic and Etiologic Research

Nutrition Studies

To address questions about links between dietary patterns and cancer incidence and mortality, particularly among ethnic minority and medically underserved populations, NCI supports a number of nutrition studies.

The Women's Health Trial: Feasibility Study in Minority Populations was initiated to assess whether ethnic minority and low-income women could be recruited into a trial in sufficient numbers to evaluate a dietary intervention and test the intervention's effects on lowering fat consumption. More than 2,000 minority and low-income women were recruited for this randomized trial. Similarly, DCCPS supports a study assessing diet and breast cancer risk among a sample of 400 black women. This Category I study seeks to "yield statistical methods for enhancing the ability to assess diet-related breast cancer risks in Black women as well as provide relevant pilot data to support future studies" (National Cancer Institute, 1998b, p. 24).

DCEG staff are investigating the relationship between fatty acids and prostate cancer risk among African-American and white males. The levels of a variety of fatty acids are being measured in plasma collected from both African-American and white men in a large, multicenter, population-based case-control study to search for relationships between fatty acid profiles and prostate cancer risk. Ethnic-group differences in these profiles and their relationship to prostate cancer will be assessed, as will the relationship between diet and fatty acid profiles. NCI has classified this research as a Category I and II study.

The Multiethnic/Minority Cohort Study of Diet and Cancer prospectively examines the relationship of dietary and other lifestyle risk factors to cancer. Investigators at the University of Hawaii at Manoa are studying a total of 215,000 African-American, Japanese-American, Hispanic, and white subjects in the western United States to assess dietary patterns and group differences. Slightly more than $1 million was allocated to this Category I activity in FY 1997. In addition, NCI staff are collaborating on analyses of the contributions of dietary and nutritional patterns to the high incidence



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement