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Veterans and Agent Orange: Update 1998 (1999)
Institute of Medicine (IOM)

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. "6 Epidemiologic Studies." Veterans and Agent Orange: Update 1998. Washington, DC: The National Academies Press, 1999.

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Veterans and Agent Orange: Update 1998

TABLE 6-3 Epidemiologic Studies—Vietnam Veterans

Reference

Study Design

Description

Study Group (N)

Comparison Group (N)a

UNITED STATES STUDIES

Ranch Hands

New Studies

Michalek et al., 1998a

Cohort

Paternal serum dioxin levels and infant death among the offspring of Ranch Hands

859 children:

323 background exposure,

267 low exposure,

269 high exposure

1,223 children

Henriksen et al., 1997

Cohort

Study of the relationship between serum dioxin and glucose and insulin levels and diabetes mellitus in Ranch Hands through 1992

989

1,276

AFHS, 1996

Cohort

Mortality update of Ranch Hands through the end of 1993 m the same cohort as AFHS (1983, 1984b, 1985, 1986, 1989, 1991a, 1995)

1,261

19,080

Michalek et al., 1998b

 

 

 

 

Henriksen et al., 1996

Cohort

Study of serum dioxin and reproductive hormones in Ranch Hands in 1982, 1985, 1987, and 1992

1,045 (participants, 1982)

474 (provided semen)

1,224 (participants, 1982)

532 (provided semen)

Studies Reviewed in Update 1996

AFHS, 1995

Cohort

Mortalּty updates of Ranch Hands tasked with herbicide spraying operations during the Vietnam conflict, compared with Air Force C-130 air and ground crew veterans in Southeast Asia who did not participate inherbicide spraying missions

1,261 (original cohort)

19,101 (original cohort)

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206