TABLE 10-1 Selected Neurobehavioral Studies of Herbicide Exposure

Reference

Study Group

Tests of Neurological Dysfunction

Exposure Measures

Comparison

Group

OCCUPATIONAL

Zober et al., 1994

158 German BASF employees

Medical record review

Chloracne and TCDD levels

161 reference comparisons

Berkley and Magee, 1963

1 farmer

Neurological examination

No

None

Todd, 1962

1 weed-sprayer

Neurological examination

No

None

Goldstein et al., 1959

2 farmers

Neurological examination

No

None

 

1 book-keeper

EMG

 

 

Baader and Bauer, 1951

10 pentachlorophenol plant workers

Record review clinical evaluation

No

None

ENVIRONMENTAL

Peper et al., 1993

19 German residents exposed to 2,3,7,8-TCDD

Neuropsychological battery and symptom questionnaires

Serum TCDD

None

VIETNAM VETERANS

Visintainer et al., 1995

151,377 Michigan veterans who served in Vietnam

No: mortality data only

No

225,651 Non-Vietnam veterans

Decoufle et al., 1992

7,924 veterans

Self-report with neurological examinations in a subset

Self-report

7,364 Non-Vietnam veterans



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