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Page 307
Addendum to Chapter 10 Table A10-1 Internal Cancer Data From Arsenic-exposure Studies Conducted In Taiwan Region Endemic To Blackfoot Disease
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TABLE A10-1 Internal Cancer Data from Arsenic-Exposure Studies Conducted in Taiwan Region Endemic to Blackfoot Diseasea
No. of
Person-Years
Bladder
Liver
Lung
Village
Wells
Arsenic Concentration, ppm
Median
M
F
M
F
M
F
M
F
3-H
1
0.010
0.010
4,159
4,043
1
6
3
1
3
5
2-1
1
0.011
0.011
3,529
3,194
0
0
0
0
0
1
0-G
5
0.010, 0.010, 0.030, 0.259, 0.770
0.030
5,388
4,861
3
2
3
3
4
5
3-5
1
0.032
0.032
7,851
7,033
3
3
5
2
6
2
3-N
1
0.032
0.032
2,689
2,392
4
3
1
1
3
1
4-7
1
0.042
0.042
10,629
10,227
0
0
4
0
0
0
6-A
1
0.045
0.045
7,716
6,820
0
0
1
1
0
0
0-J
2
0.020, 0.080
0.050
6,501
5,888
1
0
2
2
0
0
3-L
2
0.053, 0.058
0.056
6,238
5,094
3
4
3
0
5
7
4-D
1
0.060
0.060
10,107
9,227
1
2
1
1
1
2
3-P
1
0.065
0.065
6,574
5,927
0
0
3
0
2
5
6-C
1
0.073
0.073
12,767
11,937
0
1
2
0
2
0
4-8
1
0.080
0.080
11,307
10,332
1
0
3
1
2
2
0-0
1
0.100
0.100
6,895
6,392
0
0
2
2
3
1
O-E
5
0.010, 0.085, 0.110, 0.288, 0.686
0.110
5,753
5,310
6
3
3
1
4
5
0-I
7
0.020, 0.050, 0.110, 0.110, 0.190, 0.580, 0.590
0.110
4,249
3,833
0
2
1
3
3
2
4-N
2
0.073, 0.172
0.123
4,709
4,291
0
0
3
1
1
2
4-J
1
0.126
0.126
6,508
6,026
0
1
6
1
2
2
2-D
1
0.256
0.256
9,702
8,869
0
2
2
1
7
1
0-D
1
0.256
0.256
3,872
3,412
1
3
2
3
5
2
3-Q
6
0.148, 0.198, 0.242, 0.276, 0.291, 0.458
0.259
5,580
5,079
2
0
4
2
5
4
4-M
1
0.307
0.307
2,953
2,758
1
0
0
0
2
3
6-6
1
0.307
0.307
5,364
4,505
3
0
3
1
4
1
4-E
2
0.340, 0.360
0.350
3,942
3,586
0
0
1
0
0
1
4-L
2
0.310, 0.485
0.398
3,069
2,723
1
1
1
0
0
1
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No. of
Person-Years
Bladder
Liver
Lung
Village
Wells
Arsenic Concentration, ppm
Median
M
F
M
F
M
F
M
F
4-F
11
0.120, 0.170, 0.229,0.260, 0.260, 0.406,0.469, 0.485, 0.595, 0.779, 0.819
0.406
4,482
3,886
2
3
1
0
5
1
3-1
1
0.448
0.448
4,551
4,259
2
3
5
1
4
3
5-G
1
0.467
0.467
3,179
5,298
7
5
2
3
7
1
4-P
1
0.504
0.504
5,843
5,397
1
0
1
1
1
1
0-H
5
0.050, 0.394, 0.520, 0.610,1.752
0.520
4,390
4,313
3
2
4
0
4
5
4-1
47
0.020, 0.020, 0.030, 0.090, 0.100, 0.110, 0.120, 0.5200.120, 0.160, 0.190, 0.230, 0.240, 0.250, 0.270, 0.270, 0.290, 0.290, 0.350, 0.370, 0.410, 0.430, 0.450, 0.510, 0.520, 0.540, 0.560, 0.660, 0.700, 0.730, 0.740, 0.760, 0.760, 0.760, 0.780, 0.810, 0.810, 0.840, 0.840, 0.850, 0.850, 0.850, 0.870, 0.880, 0.900, 0.930, 0.940, 0.970
0.520
4,870
4,432
2
2
1
0
3
5
3-J
2
0.529, 0.529
0.529
8,454
8,689
4
8
3
1
6
5
3-S
2
0.480, 0.595
0.538
4,287
3,667
4
3
7
0
8
4
3-9
1
0.544
0.544
3,655
3,413
0
1
1
1
1
0
2-2
10
0.560, 0.580, 0.580, 0.590, 0.597, 0.600, 0.618, 0.620, 0.650, 0.704
0.599
9,059
7,977
2
2
9
5
8
5
4-G
2
0.620, 0.680
0.650
2,425
2,108
2
0
0
0
2
2
5-4
2
0.630, 0.735
0.683
3,155
2,983
1
1
2
1
5
2
2-M
2
0.435, 0.950
0.693
11,123
11,263
9
9
6
4
14
4
0-F
5
0.415, 0.660, 0.694, 0.720, 0.749
0.694
7,010
5,720
5
1
8
3
2
9
3-R
5
0.397, 0.440, 0.698, 0.750,1.010
0.698
4,310
3,576
3
6
3
2
6
7
3-M
4
0.221, 0.329, 1.105,1.411
0.717
5,815
4,877
0
1
2
0
0
0
2-N
3
0.560, 0.934, 0.960
0.934
8,341
8,342
7
10
8
2
4
4
aData from Wu et al. 1989; Chen et al. 1992.
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References Chen, C.J., C.W. Chen, M.M. Wu, and T.L. Kuo. 1992. Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water. Br. J. Cancer 66:888-892.
Wu, M.M., T.L. Kuo, Y.H. Hwang, and C.J. Chen. 1989. Dose-response relation between arsenic concentration in well water and mortality from cancers and vascular diseases. Am. J. Epidemiol. 130:1123-1232.
Representative terms from entire chapter:
blackfoot disease