The following HTML text is provided to enhance online
readability. Many aspects of typography translate only awkwardly to HTML.
Please use the page image
as the authoritative form to ensure accuracy.
A fragment (also known as C3a) of complement C3 that causes cellular release of histamine.
An immunoglobulin protein produced by the immune system, designed to bind to a specific single antigen. Antibodies neutralize foreign antigens; form immune complexes; activate complement; sensitize target cells, mast cells, and basophils; and initiate opsonization.
Any substance (or molecule) capable of inducing a specific immune response. Antigens include a wide variety of plant and microorganism components or toxins.
An acute-phase reactant plasma glycoprotein.
Dermal skin test reactions (characteristic of Type III hypersensitivities), that occur during a 4–12 h interval.
Any disease caused by the immune system's erroneous and destructive actions on the body's own tissues, such as thyroiditis, myocarditis, glomerulonephritis, and lupus erythematosus.
A white blood cell (WBC) with granules that can be stained by basic dyes. Basophils participate in inflammatory processes and in allergic and hypersensitivity reactions by releasing histamine.
B-cells (or B-lymphocytes).
Thymus-independent, bursa-equivalent lymphocytes produced by bone marrow to populate all lymphoid organs and tissues. They are capable of producing antibodies and maturing into plasma cells. B-cells express antibody on their surfaces that can respond to foreign protein, polysaccharide, and lipid antigens in soluble form.
A proteinase enzyme released by polymorphonuclear leukocytes during inflammation.
Antigen-specific and nonspecific immunity provided by the direct localized cellular activity of T-lymphocytes and natural killer cells. Specific cells include T–helper cells (Th) and T–cytotoxic cells (Tc); nonspecific cells include macrophages, neutrophils, eosinophils, and NK-cells.
Helper T-cells recognized by the presence of cluster of differentiation antigen 4 on their exterior cell surfaces.
Suppressor T-cells recognized by the presence of cluster of differentiation antigen 8 on their exterior cell surfaces.