implementation affect success, and the most successful guidelines are those with internal development, specific educational interventions, patient-specific reminders at the time of consultation, and a system to hold providers accountable for adherence. Studies of the impact of oncology guidelines have often not included a concurrent control group that was not exposed to the guideline intervention, which makes it difficult to attribute change to guideline implementation.
TABLE 6.8
Compliance with National Guidelines in Italy as Measured by Chart Audit, 1987
|
Recommendation
|
Compliance (%)
|
|
Breast Cancer
|
Gold standard: 100%
|
|
Bilateral mammography
|
61
|
|
Clinical stage
|
37
|
|
Pathological stage
|
60
|
|
Evaluation of axillary lymph nodes
|
89
|
|
Avoidance of radical mastectomy if T < 2.0 cm
|
84
|
|
Radiotherapy after quadrantectomy
|
65
|
|
Adjuvant chemotherapy started at <4 weeks
|
52
|
|
Polychemotherapy if <50, + lymph nodes
|
71
|
|
Chemotherapy delivered at full dosage
|
86
|
|
Colon Cancer
|
|
CEA levels and liver ultrasound
|
40
|
|
TNM staging
|
78
|
|
Search for intra-abdominal metastasis
|
67
|
|
Information on resection borders
|
48
|
|
Evaluation of regional lymph nodes
|
66
|
|
Miles resection in lower rectal cancer
|
68
|
|
Radiotherapy in rectal and rectosigmoid cancer
|
11
|
|
No adjuvant chemotherapy in colon cancer
|
79
|
|
If chemotherapy, 5-FU-containing regimen
|
90
|
|
Ovarian Cancer
|
|
Full information on tumor grading
|
30
|
|
Staging including abdominal echography
|
75
|
|
Histologic type according to standard classifications
|
89
|
|
Chest x-ray
|
97
|
|
Evaluation of residual tumor
|
45
|
|
Disease stage according to standard classification
|
85
|
|
Alkylating agent as part of chemotherapy for early disease
|
18
|
|
Cisplatin-containing regimens for advanced disease
|
34
|
|
Monitoring of toxicity while on chemotherapy
|
91
|
|
Monitoring of nephrotoxicity while on chemotherapy
|
84
|
|
NOTE: CEA = carcinoembryonic antigen; 5-FU = 5-fluorouracil; TNM = tumor-node-mestastasis.
SOURCE: Grilli et al., 1991.
|