1. Breast cancer:
  • Care, costs, and outcomes of local breast cancer
  • Care, costs, and outcomes of breast cancer: elderly African Americans
  • Experiences of low-income women with breast cancer
  • Prostate cancer:
    • PORT-II for prostatic diseases
    • Enhanced accuracy of MI for staging prostate cancer
    • Comparison of treatment efficacy for prostate cancer
    • Treatment choices and outcomes in prostate cancer
    • Assessing therapies for BPH (benign prostatic hyperplasia) and localized prostate cancer
  • Other cancers:
    • Patterns of care and outcomes for colon cancer
    • Computerized decision support for posttransplant care
    • Quality outcomes in subacute and home care programs
    • Practice variations in pain control at the end of life
    • Using cancer registries to assess quality of cancer care
    • Internet multimedia cancer patient education system
    • Risk adjustment methods for hysterectomy complications

    SOURCE: Wendy Perry, AHCPR, personal communication to Maria Hewitt, December 1998.

    Evidence-Based Practice Program. The Evidence-Based Practice Program supports literature syntheses on clinical effectiveness, a resource for developing clinical practice guidelines or performance measures. Two cancer-related topics were among the first 12 topics assigned to the evidence-based practice centers: testosterone suppression treatment for advanced prostate cancer and evaluation of cervical cytology. In addition, two assessments will be completed in 1999: (1) an assessment of the management of cancer pain and (2) an analysis of the use of erythropoietin in hematology and oncology.

    CONQUEST. CONQUEST (Computerized Needs-Oriented QUality Measurement Evaluation System) is a database of clinical performance measures, a resource for quality monitoring activities. Included are measures related to the management of several cancers (i.e., colorectal, lung, prostate, breast), the use of screening tests (i.e., mammography, Pap smear), and cigarette use.

    Patient Outcomes Research Teams (PORTs). PORTs conduct research and disseminate findings related to common disorders. Two of the 14 conditions funded to date relate to cancer, prostate disease, and local breast cancer.

    Clinical Trials. AHCPR's budget is insufficient to permit sole funding of major randomized clinical trials, although it has on a few occasions collaborated with other agencies (e.g., the Department



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