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TABLE 7

LD50 of Arsine after Intraperitoneal Injection (Levvy, 1946)

Species

LD50 mg/kg

Mouse

3.0

Rabbit

2.5

Cat

2.0–2.5

Sheep

3.0

TABLE 8

Acute Toxicity of Arsine in Mice After Inhalation (Levvy, 1947)a

Concentration

Duration of Exposure

Mortality,a %

Estimated Duration for 50% Mortality

mg/L

ppm

2.5

783

0.50 min

93

0.40 min

 

 

0.33 min

20

 

1.0

313

1.25 min

57

1.18 min

 

 

0.83

13

 

0.50

157

10 min

100

2.4 min

 

 

5 min

93

 

 

 

2.5 min

57

 

 

 

1.7 min

0

 

0.25

78.3

15 min

70

12 min

 

 

9 min

33

 

0.10

31.3

70 min

100

50 min

 

 

50 min

50

 

0.025

7.8

30 h

100

24 h

 

 

27 h

50

 

 

 

24 h

50

 

 

 

21 h

50

 

 

 

18 h

0

 

 

 

15 h

0

 

aThirty mice in each experiment with arsine at 0.1 to 2.5 mg/L; six mice used in each experiment with arsine at 0.025 mg/L.



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