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APPE .~131 X ~ EXCERPTS FROM BZ DATA Contrac t DA-18-108-405-C~-82 6 Hazelton Laboratories Falls Church, Virginia CONTENTS I. Basic Screening Program I. Preclinical Pharmacology Program* a. Preclinical Pharmacology Study - Rats b. Preclinical Pharmacology Study - Dogs c. Preclinical Pharmacology Study - Monkeys III. Aditional Effort Requirements a. Ef feet s on Operant Behavior - -Monkeys b. Conditional Avoidance Response Test - Dogs c. Drug Antagonism Study - Monkeys d. Dose Regressi on Study - Dogs e. Pilot Inhalation Study - Monkeys f . Modif fed Po si t ive Re ~ Of ore ement Schedule g . Tentat ive Posi t ive Rei Of o cc ement Schedul e h. Do se Regre ssion S tudy - Monkeys i . Conditioned Avoidance Re spouse Sensitivity Test - Dogs j. Sustained Physical Exercise Sensitivity Test - Dogs k. Progress Report on the Non-Discriminated Avoidance Re sponse Te s ~ I. Current Status Summary Report m. Visual Discrimination Sensitivity Test - Monkeys n. Tolerance Study in the Conditioned Avoidance Response Test - Dogs o. Multiple Stimulus Conditioned Avoidance Response Test - Dogs p. Progress Report on the Nondiscriminated Avoidance Response Test q. Tolerance Study in the Visual Discrimination Test - Monkeys r. Progress Report on the Three Stimulus Visual Discrimination Test - Monkeys s. Antagonism of the Effects of BZ in the Sidman Nondiscriolinated Avoidance Re spouse Test - Monkey Tolerance Study in the Sustained Physical Exercise Test - Dogs u. Antagonism of the Ef fects of BZ in the Sidman Nondiscriminatet Avoidance Response Test - Monkey v. Cross-Toleranc e S tudy in the Sustained Physical Exerc ise Tes t - Dogs w. Visual Discrimination Relative Sensitivity Study Monkey s F 1